Evidence map›Paper›PMID 39241195›Full record

ReviewBlood2025

Allogeneic hematopoietic cell transplantation for acute myeloid leukemia in adults over 70 years old.

Roland B Walter, Victoria Potter, Charles Craddock

Abstract readReview
In one paragraph

Review in Blood, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Review
  3. Significance of CD34Transplantation and cellular therapy · 2026
    Article
  4. Article
  5. Review
  6. Allogeneic hematopoietic cell transplantation in vulnerable populations: Advances and perspectives.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2025
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Roland B WalterTranslational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA.ORCID 0000-0002-9268-3341
Victoria PotterDepartment of Haematological Medicine, Kings College Hospital National Health Service (NHS) Foundation Trust, London, United Kingdom.ORCID 0000-0002-7108-5297
Charles CraddockCentre for Clinical Haematology, University Hospital Birmingham NHS Trust, Birmingham, United Kingdom.ORCID 0000-0001-5041-6678

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractThe advent of reduced-intensity conditioning regimens, improvements in graft-versus-host disease prophylaxis, and better supportive care have permitted increasing use of allogeneic hematopoietic cell transplantation (allo-HCT) in adults aged ≥70 years with acute myeloid leukemia. However, although potentially curative, nonrelapse mortality and relapse represent the main causes of treatment failure, highlighting the importance of refining both patient selection and transplant strategies. At the same time, continuously evolving nontransplant therapies and transplant technologies mandate prospective trials (re-)examining the role of allo-HCT and its optimal delivery.

Indexed as

Hematopoietic Stem Cell TransplantationLeukemia, Myeloid, AcuteAgedGraft vs Host DiseaseHumansTransplantation ConditioningTransplantation, Homologous

Identifiers

PMID39241195
PMCPMC12226756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.