Evidence map›Paper›PMID 39241192›Full record

ArticleACS applied bio materials2024

Development and Use of Human Recombinant

Edwin J Baldelomar, Hanwen Zhang, Daniel Thorek, Jennifer R Charlton, Patrick D Walker, Leslie D Wilson, Kasey C Emoto, Veronica Clavijo Jordan, David E Reichert, Kooresh Shoghi and 1 more

Abstract read
In one paragraph

Article in ACS applied bio materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Are noninvasive measurements of nephron number achievable in humans?Current opinion in nephrology and hypertension · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Edwin J BaldelomarXN Biotechnologies, LLC, St. Louis, Missouri 63110, United States.ORCID 0000-0002-3482-373X
Hanwen ZhangMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri 63110, United States.
Daniel ThorekMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri 63110, United States.ORCID 0000-0003-2437-1239
Jennifer R CharltonDepartment of Pediatrics, Division of Nephrology, University of Virginia, Charlottesville, Virginia 22904, United States.
Patrick D WalkerArkana Laboratories, Little Rock, Arkansas 72211, United States.
Leslie D WilsonDivision of Comparative Medicine, Washington University in St. Louis, St. Louis, Missouri 63110, United States.
Kasey C EmotoDepartment of Biology, University of Hawaii at Manoa, Honolulu, Hawai'i 96822, United States.
Veronica Clavijo JordanAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital/Harvard Medical School, Charlestown, Massachusetts 02115, United States.ORCID 0000-0002-1468-164X
David E ReichertMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri 63110, United States.ORCID 0000-0003-3432-8998
Kooresh ShoghiMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri 63110, United States.
Kevin M BennettMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri 63110, United States.

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Single-Cell Epigenomics, Transcriptomics, and Bioinformatics CoreP50DK096373 · NIDDK · UNIVERSITY OF VIRGINIA · PI Silvia Medrano · 2012 to 2026
$13.8M
Washington University Institute of Clinical and Translational Sciences (TL1)TL1TR002344 · NCATS · WASHINGTON UNIVERSITY · PI Jay F. Piccirillo · 2017 to 2026
$8.5M
94 TESLA MR SCANNER FOR MURINE IMAGING: IMAGINGS10RR019911 · NCRR · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI BERR, STUART S · 2005 to 2005
$2.0M
Comprehensive MRI-based evaluation of human renal microstructureR01DK111861 · NIDDK · UNIVERSITY OF VIRGINIA · PI BENNETT, KEVIN M, CHARLTON, JENNIFER R · 2017 to 2020
$1.8M
Cellular and Molecular Mechanisms of Fatty Liver DiseaseR01DK111052 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI YU, LIQING · 2016 to 2019
$1.4M
Noninvasive MRI techniques to detect pathology in murine models of renal diseaseR01DK110622 · NIDDK · WASHINGTON UNIVERSITY · PI BENNETT, KEVIN M, CHARLTON, JENNIFER R · 2017 to 2019
$1.0M
Translational imaging tools to nondestructively measure nephron massR41DK129138 · NIDDK · XN BIOTECHNOLOGIES, LLC · PI BENNETT, KEVIN M · 2021 to 2021
$300k
NCATS NIH HHS TL1 TR002344NCATS NIH HHS UL1 TR002345NCRR NIH HHS S10 RR019911NIDDK NIH HHS P50 DK096373NIDDK NIH HHS R01 DK110622NIDDK NIH HHS R01 DK111052NIDDK NIH HHS R01 DK111861NIDDK NIH HHS R41 DK129138
6 · The paper itself

Abstract

In this work, we develop recombinant human cationic ferritin (rHCF) as a contrast agent to detect glomeruli in the kidney using positron emission tomography (PET). We first expressed recombinant human ferritin (rHF) in

Indexed as

Biocompatible MaterialsContrast MediaCopper RadioisotopesKidney GlomerulusMaterials TestingPositron-Emission TomographyRecombinant ProteinsAnimalsFerritinsHumansMiceParticle SizeBiocompatible MaterialsContrast MediaCopper-64Copper RadioisotopesFerritinsRecombinant ProteinsCFE-MRIGlomerulusHuman Recombinant FerritinKidney Nephron NumberPositron Emission Tomography

Identifiers

PMID39241192
PMCPMC12172436

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.