Evidence map›Paper›PMID 39241107›Full record

ArticlePLoS biology2024

Syllable processing is organized in discrete subregions of the human superior temporal gyrus.

Daniel R Cleary, Youngbin Tchoe, Andrew Bourhis, Charles W Dickey, Brittany Stedelin, Mehran Ganji, Sang Heon Lee, Jihwan Lee, Dominic A Siler, Erik C Brown and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PLoS biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Daniel R ClearyDepartment of Neurosurgery, University of California San Diego, La Jolla, California, United States of America.ORCID 0000-0001-7112-4519
Youngbin TchoeDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, California, United States of America.
Andrew BourhisDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, California, United States of America.
Charles W DickeyNeurosciences Graduate Program, University of California, San Diego, La Jolla, California, United States of America.
Brittany StedelinDepartment of Neurological Surgery, Oregon Health & Science University, Portland, Oregon, United States of America.
Mehran GanjiDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, California, United States of America.
Sang Heon LeeDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, California, United States of America.
Jihwan LeeDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, California, United States of America.
Dominic A SilerDepartment of Neurological Surgery, Oregon Health & Science University, Portland, Oregon, United States of America.
Erik C BrownDepartment of Neurological Surgery, Oregon Health & Science University, Portland, Oregon, United States of America.
Burke Q RosenDepartment of Neuroscience, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Erik KaestnerCenter for Multimodal Imaging and Genetics, University of California San Diego, La Jolla, California, United States of America.
Jimmy C YangDepartment of Neurology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Daniel J SoperDepartment of Neurology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Seunggu Jude HanDepartment of Neurological Surgery, Oregon Health & Science University, Portland, Oregon, United States of America.
Angelique C PaulkDepartment of Neurology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Sydney S CashDepartment of Neurology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Ahmed M RaslanDepartment of Neurological Surgery, Oregon Health & Science University, Portland, Oregon, United States of America.
Shadi A DayehDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, California, United States of America.
Eric HalgrenDepartment of Radiology, University of California San Diego, La Jolla, California, United States of America.

Funding

Thin, High-Density, High-Performance, Depth and Surface Microelectrodes for Diagnosis and Treatment of EpilepsyUG3NS123723 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAYEH, SHADI · 2021 to 2025
$9.5M
From ion channel dynamics to human EEG and MEG: multiscale neuronal models validated by human dataRF1MH117155 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BAZHENOV, MAKSIM V, CASH, SYDNEY S · 2018 to 2018
$3.7M
Bringing Light to Functional Mapping in Resective NeurosurgeryDP2EB029757 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAYEH, SHADI · 2019 to 2019
$2.4M
Integration of High Definition Display Technologies with Platinum Nanorod Microelectrodes for Large Scale in-vivo Recording and StimulationR01NS123655 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAYEH, SHADI · 2021 to 2021
$2.0M
Effects of intrinsic and drug-induced neuromodulation on functional brain imagingR01DA050159 · NIDA · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI DEVOR, ANNA · 2020 to 2024
$1.9M
Seizure focus delineation using spontaneous and stimulus evoked EEG featuresK24NS088568 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CASH, SYDNEY S · 2015 to 2019
$923k
High-density microgrid development for human neural interface devicesF32MH120886 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CLEARY, DANIEL R · 2019 to 2019
$73k
NIBIB NIH HHS DP2 EB029757NIDA NIH HHS R01 DA050159NIMH NIH HHS F32 MH120886NIMH NIH HHS RF1 MH117155NINDS NIH HHS K24 NS088568NINDS NIH HHS R01 NS123655NINDS NIH HHS UG3 NS123723
6 · The paper itself

Abstract

Modular organization at approximately 1 mm scale could be fundamental to cortical processing, but its presence in human association cortex is unknown. Using custom-built, high-density electrode arrays placed on the cortical surface of 7 patients undergoing awake craniotomy for tumor excision, we investigated receptive speech processing in the left (dominant) human posterior superior temporal gyrus. Responses to consonant-vowel syllables and noise-vocoded controls recorded with 1,024 channel micro-grids at 200 μm pitch demonstrated roughly circular domains approximately 1.7 mm in diameter, with sharp boundaries observed in 128 channel linear arrays at 50 μm pitch, possibly consistent with a columnar organization. Peak latencies to syllables in different modules were bimodally distributed centered at 252 and 386 ms. Adjacent modules were sharply delineated from each other by their distinct time courses and stimulus selectivity. We suggest that receptive language cortex may be organized in discrete processing modules.

Indexed as

Speech PerceptionTemporal LobeAcoustic StimulationAdultBrain MappingFemaleHumansLanguageMaleMiddle Aged

Identifiers

PMID39241107
PMCPMC11410217

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.