Evidence map›Paper›PMID 39240522›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

In Vivo Imaging of Rodent Retina in Retinal Disease.

Avigail Beryozkin, Leah C Byrne

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Avigail BeryozkinDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.
Leah C ByrneDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA. lbyrne@pitt.edu.

Funding

Virus Production and Manipulation of Protein/Gene Expression ModuleP30EY008098 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Ethan A Rossi · 1989 to 2026
$17.8M
A Massive Library of AAVs to Target Transcriptionally-Defined Primate Cell TypesUG3MH120094 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STAUFFER, WILLIAM RICHARD · 2019 to 2021
$5.8M
NEI NIH HHS P30 EY008098NIMH NIH HHS UG3 MH120094
6 · The paper itself

Abstract

High-quality imaging of the retina is crucial to the diagnosis and monitoring of disease, as well as for evaluating the success of therapeutics in human patients and in preclinical animal models. Here, we describe the basic principles and methods for in vivo retinal imaging in rodents, including fundus imaging, fluorescein angiography, optical coherence tomography, fundus autofluorescence, and infrared imaging. After providing a concise overview of each method and detailing the retinal diseases and conditions that can be visualized through them, we will proceed to discuss the advantages and disadvantages of each approach. These protocols will facilitate the acquisition of optimal images for subsequent quantification and analysis. Additionally, a brief explanation will be given regarding the potential results and the clinical significance of the detected abnormalities.

Indexed as

Disease Models, AnimalFluorescein AngiographyRetinaRetinal DiseasesTomography, Optical CoherenceAnimalsFundus OculiHumansMiceOptical ImagingRatsRodentiaFluorescein angiographyFundus autofluorescenceFundus imagingInfrared imagingOptical coherence tomographyRetinal diseasesRetinal imagingRodents

Identifiers

PMID39240522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.