Evidence map›Paper›PMID 39240505›Full record

ArticleCardiovascular intervention and therapeutics2025

Hemodynamic effect of supra-annular implantation of SAPIEN 3 balloon expandable valve.

Masakazu Yasuda, Kazuki Mizutani, Kyohei Onishi, Naoko Onishi, Kosuke Fujita, Masafumi Ueno, Atsushi Okamura, Yoshitaka Iwanaga, Genichi Sakaguchi, Gaku Nakazawa

Abstract read
In one paragraph

Article in Cardiovascular intervention and therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The "floating" valve, a modified bioroot Bentall procedure.Frontiers in cardiovascular medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Masakazu YasudaDivision of Cardiology, Sakurabashi Watanabe Advanced Healthcare Hospital, OSAKA, Japan.
Kazuki MizutaniDepartment of Cardiology, Sapporo Cardio vascular Clinic, 8-1, Kita 49 jyo, Higashi 16 jyo, Higashi-ku, Sapporo, 007-0849, Japan. ikki1127@gmail.com.ORCID http://orcid.org/0000-0001-7206-4538
Kyohei OnishiDivision of Cardiology, Department of Internal Medicine, Kindai University Faculty of Medicine, OSAKA, Japan.
Naoko OnishiDivision of Cardiology, Department of Internal Medicine, Kindai University Faculty of Medicine, OSAKA, Japan.
Kosuke FujitaDivision of Cardiology, Department of Internal Medicine, Kindai University Faculty of Medicine, OSAKA, Japan.
Masafumi UenoDivision of Cardiology, Department of Internal Medicine, Kindai University Faculty of Medicine, OSAKA, Japan.
Atsushi OkamuraDivision of Cardiology, Sakurabashi Watanabe Advanced Healthcare Hospital, OSAKA, Japan.
Yoshitaka IwanagaDivision of Cardiology, Sakurabashi Watanabe Advanced Healthcare Hospital, OSAKA, Japan.
Genichi SakaguchiDepartment of Cardiovascular Surgery, Kindai University Faculty of Medicine, OSAKA, Japan.
Gaku NakazawaDivision of Cardiology, Department of Internal Medicine, Kindai University Faculty of Medicine, OSAKA, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hemodynamic impact of the implantation depth for balloon-expandable valves is under-investigated, especially with higher implantation techniques. We assessed the hemodynamic performance of supra-annular SAPIEN 3 valve implantation. This retrospective study involved consecutive patients who underwent transcatheter aortic valve replacement (TAVR) using the SAPIEN 3. The device implantation depth and transcatheter heart valve (THV) leaflet-nadir position were angiographically analyzed, and supra-annular implantation was defined as a higher leaflet-nadir position than the original annular line. The Doppler hemodynamic status was evaluated at patient discharge. Among 184 patients, 120 (65%) underwent supra-annular implantation, and their mean implantation depth was significantly lower than that of intra-annular implantation (1.1 vs. 5.2 mm, p < 0.001). No patients developed valve embolization or coronary occlusion, and none required the TAV-in-TAV procedure. Two (1.6%) patients in the supra-annular implantation group had a mild or greater paravalvular leak. Echocardiography demonstrated that supra-annular implantation had better hemodynamic performance, showing a larger indexed effective orifice area (iEOA) compared with intra-annular implantation (1.09 vs. 0.97 cm

Indexed as

Aortic ValveAortic Valve StenosisHeart Valve ProsthesisHemodynamicsTranscatheter Aortic Valve ReplacementAgedAged, 80 and overFemaleHumansMaleProsthesis DesignRetrospective StudiesTreatment OutcomeBalloon expandable valveHemodynamic performanceSupra-annular implantationTranscatheter aortic valve replacement

Identifiers

PMID39240505
PMCPMC11723897

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.