Evidence map›Paper›PMID 39240390›Full record

ReviewMolecular biology reports2024

Role of homeobox genes in cancer: immune system interactions, long non-coding RNAs, and tumor progression.

Saade Abdalkareem Jasim, Shireen Hamid Farhan, Irfan Ahmad, Ahmed Hjazi, Ashwani Kumar, Mohammed Abed Jawad, Atreyi Pramanik, Farag M A Altalbawy, Salim B Alsaadi, Munther Kadhim Abosaoda

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Toward a cell-type-specific lung HOX code.Frontiers in cell and developmental biology · 2026
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Saade Abdalkareem JasimMedical Laboratory Techniques Department, Al-Maarif University College, Anbar, Iraq. saade.a.j@uoa.edu.iq.
Shireen Hamid FarhanBiotechnology Department, College of Applied Science, Fallujah University, Al-Fallujah, Iraq.
Irfan AhmadDepartment of Clinical Laboratory Sciences, College of Applied Medical Science, King Khalid University, Abha, Saudi Arabia.
Ahmed HjaziDepartment of Medical Laboratory, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, 11942, Al-Kharj, Saudi Arabia.
Ashwani KumarDepartment of Life Sciences, School of Sciences, Jain (Deemed-to-Be) University, Bengaluru, Karnataka, 560069, India.
Mohammed Abed JawadDepartment of Pharmaceutics, Al-Nisour University College, Baghdad, Iraq.
Atreyi PramanikSchool of Applied and Life Sciences, Division of Research and Innovation, Uttaranchal University, Dehradun, Uttarakhand, India.
Farag M A AltalbawyDepartment of Chemistry, University College of Duba, University of Tabuk, Tabuk, Saudi Arabia.
Salim B AlsaadiDepartment of Pharmaceutics, Al-Hadi University College, Baghdad, 10011, Iraq.
Munther Kadhim AbosaodaCollege of Pharmacy, the Islamic University, Najaf, Iraq.

Funding

Deanship of Scientific Research, King Khalid University R.G.P.1/323/44
6 · The paper itself

Abstract

The intricate interplay between Homeobox genes, long non-coding RNAs (lncRNAs), and the development of malignancies represents a rapidly expanding area of research. Specific discernible lncRNAs have been discovered to adeptly regulate HOX gene expression in the context of cancer, providing fresh insights into the molecular mechanisms that govern cancer development and progression. An in-depth comprehension of these intricate associations may pave the way for innovative therapeutic strategies in cancer treatment. The HOX gene family is garnering increasing attention due to its involvement in immune system regulation, interaction with long non-coding RNAs, and tumor progression. Although initially recognized for its crucial role in embryonic development, this comprehensive exploration of the world of HOX genes contributes to our understanding of their diverse functions, potentially leading to immunology, developmental biology, and cancer research discoveries. Thus, the primary objective of this review is to delve into these aspects of HOX gene biology in greater detail, shedding light on their complex functions and potential therapeutic applications.

Indexed as

Disease ProgressionGene Expression Regulation, NeoplasticGenes, HomeoboxImmune SystemNeoplasmsRNA, Long NoncodingAnimalsHumansRNA, Long NoncodingHox gene familyImmune systemlncRNAsncRNAsTumor progression

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.