Evidence map›Paper›PMID 39240328›Full record

ArticleBioinformatics (Oxford, England)2024

SCMeTA: a pipeline for single-cell metabolic analysis data processing.

Xingyu Pan, Siyuan Pan, Murong Du, Jinlei Yang, Huan Yao, Xinrong Zhang, Sichun Zhang

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Living single-cell metabolomicsChemical science · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xingyu PanDepartment of Chemistry, Tsinghua University, Beijing 100084, China.ORCID 0009-0002-6704-2224
Siyuan PanDepartment of Chemistry, Tsinghua University, Beijing 100084, China.
Murong DuDepartment of Chemistry, Tsinghua University, Beijing 100084, China.
Jinlei YangDepartment of Chemistry, Tsinghua University, Beijing 100084, China.
Huan YaoDivision of Chemical Metrology and Analytical Science, National Institute of Metrology China, Beijing 100029, China.
Xinrong ZhangDepartment of Chemistry, Tsinghua University, Beijing 100084, China.
Sichun ZhangDepartment of Chemistry, Tsinghua University, Beijing 100084, China.ORCID 0000-0003-3439-8523

Funding

Ministry of Science and Technology of China 2022YFF0710200National Natural Science Foundation of China 22227803
6 · The paper itself

Abstract

summaryTo address the challenges in single-cell metabolomics (SCM) research, we have developed an open-source Python-based modular library, named SCMeTA, for SCM data processing. We designed standardized pipeline and inter-container communication format and have developed modular components to adapt to the diverse needs of SCM studies. The validation was carried out on multiple SCM experiment data. The results demonstrated significant improvements in batch effects, accuracy of results, metabolic extraction rate, cell matching rate, as well as processing speed. This library is of great significance in advancing the practical application of SCM analysis and makes a foundation for wide-scale adoption in biological studies. AVAILABILITY AND IMPLEMENTATION: SCMeTA is freely available on https://github.com/SCMeTA/SCMeTA and https://doi.org/10.5281/zenodo.13569643.

Indexed as

MetabolomicsSingle-Cell AnalysisSoftwareHumans

Identifiers

PMID39240328
PMCPMC11401741

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.