Evidence map›Paper›PMID 39239977›Full record

ReviewJournal of the European Academy of Dermatology and Venereology : JEADV2025

Considerations for defining and diagnosing generalized pustular psoriasis.

Vimal H Prajapati, Charles W Lynde, Melinda J Gooderham, H Chih-Ho Hong, Mark G Kirchhof, Perla Lansang, Julien Ringuet, Irina Turchin, Ron Vender, Jensen Yeung and 1 more

Abstract readReview
In one paragraph

Review in Journal of the European Academy of Dermatology and Venereology : JEADV, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. Review
  6. Review
  7. Review
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  10. Considerations for defining and diagnosing generalized pustular psoriasis.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vimal H PrajapatiDivision of Dermatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0002-8315-2522
Charles W LyndeLynde Dermatology, Probity Medical Research, Markham and Department of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-9163-5463
Melinda J GooderhamSKiN Health, Probity Medical Research, Queen's University, Peterborough, Ontario, Canada.ORCID https://orcid.org/0000-0001-8926-0113
H Chih-Ho HongDivision of Dermatology and Skin Science, University of British Columbia, Surrey, British Columbia, Canada.ORCID https://orcid.org/0000-0001-9963-8319
Mark G KirchhofDivision of Dermatology, Faculty of Medicine, University of Ottawa, and the Ottawa Hospital, Ottawa, Ontario, Canada.ORCID https://orcid.org/0000-0002-4015-8377
Perla LansangDivision of Dermatology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Julien RinguetCentre de Recherche Dermatologique du Québec (CRDQ), Québec, Quebec, Canada.ORCID https://orcid.org/0000-0002-6773-4645
Irina TurchinBrunswick Dermatology Center and Probity Medical Research, Fredericton, New Brunswick, Canada.ORCID https://orcid.org/0000-0001-8654-9050
Ron VenderDivision of Dermatology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0000-0002-2624-2724
Jensen YeungDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-7318-5515
Kim A PappDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-9557-3642

Funding

Boehringer Ingelheim
6 · The paper itself

Abstract

Generalized pustular psoriasis (GPP) is a rare, chronic skin disease, characterized by widespread pustules and erythema, often accompanied with systemic signs and symptoms. GPP flares occur episodically but may be protracted. Left untreated, GPP can be life-threatening. Despite being first reported over 100 years ago, definitions and diagnostic criteria for GPP have been inconsistent and varied due, in part, to its rarity and a limited understanding of its pathogenesis. As such, many patients with GPP face delays in diagnosis and subsequent treatment. This manuscript aims to increase the recognition of GPP and provide foundational considerations to aid in the definition and diagnosis of this disease.

Indexed as

PsoriasisDiagnosis, DifferentialHumans

Identifiers

PMID39239977
PMCPMC11851258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.