Evidence map›Paper›PMID 39239052›Full record

ArticleAnnals of medicine and surgery (2012)2024

Insights into the clinical impact of complete blood cell inflammatory markers on body composition variations and fatty liver grading in Iranian adults undergoing bariatric surgery: a retrospective longitudinal study.

Hanieh Radkhah, Ali Alirezaei, Peyvand Parhizkar, Razieh Khalooeifard, Batoul Khoundabi, Khosrow Najjari, Mohammad Talebpour, Reza Hajabi

Abstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Hanieh RadkhahSina Hospital, Department of Internal Medicine.
Ali AlirezaeiSchool of Nutritional Sciences and Dietetics.
Peyvand ParhizkarTehran University of Medical Sciences.
Razieh KhalooeifardDepartment of Clinical Nutrition School of Nutritional Sciences and Dietetics.ORCID https://orcid.org/0000-0001-6184-1952
Batoul KhoundabiIran Helal Institute of Applied-Science and Technology, Red Crescent Society of Iran, Research Center for Health Management in Mass Gathering, Red Crescent Society of the Islamic Republic of Iran, Tehran, Iran.
Khosrow NajjariDepartment of General Surgery.
Mohammad TalebpourDepartment of General Surgery.
Reza HajabiDepartment of General Surgery, School of Medicine, Sina Hospital, Tehran University of Medical Sciences.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In bariatric surgery, inflammatory biomarkers predict outcomes. Limited research on complete blood cell (CBC) markers stresses the need for correlation study. This research explores links between CBC inflammatory markers, body changes, and fatty liver grades in Iranian bariatric patients. Materials and methods: This retrospective longitudinal study examined 237 bariatric surgery patients who satisfied the inclusion criteria and were deemed eligible for participation. These criteria encompassed patients who had undergone sleeve or mini-bypass surgery and were aged between 18 and 65 years. The study gathered demographic data, pre and post-surgery changes in CBC inflammatory biomarkers [neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR), mean platelet volume (MPV), MPV-to-platelet count ratio (MPV/PC), and red cell distribution width (RDW)] and fatty liver grades. Additionally, it recorded pre and post-surgery changes in body composition, such as weight, muscle mass (MM), fat mass (FM), and fat-free mass (FFM). Results: The pre-surgery RDW marker significantly associated with FM changes, highlighting its predictive nature. While no significant association was found between changes in patients' fatty liver grade and baseline marker values, it's worth noting that individuals with higher MM at 3 months achieved a fatty liver grade of zero. Also, at 6 months, higher FFM and MM were also associated with reaching a fatty liver grade of zero. Conclusions: While the retrospective design of this study limits its findings to existing clinical data, future prospective research should collect additional samples, extend the observation time, and examine the long-term predictive value of these markers.

Indexed as

bariatric surgerybody compositionfatty liverinflammatory biomarkers

Identifiers

PMID39239052
PMCPMC11374248

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.