Evidence map›Paper›PMID 39238795›Full record

ArticleAnnals of gastroenterology

Transcatheter arterial embolization for small-bowel bleeding: technical and clinical outcomes and risk factors for early recurrent bleeding.

Quinten Verhalleman, Marc Miserez, Annouschka Laenen, Lawrence Bonne, Eveline Claus, Jo Peluso, Alexander Wilmer, Geert Maleux

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Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Quinten VerhallemanDepartment of Radiology, University Hospitals KU Leuven (Quinten Verhalleman, Lawrence Bonne, Eveline Claus, Jo Peluso, Geert Maleux).
Marc MiserezDepartment of Abdominal Surgery, University Hospitals KU Leuven (Marc Miserez).
Annouschka LaenenDepartment of Biostatistics and Statistical Bioinformatics, University Hasselt and University Hospitals KU Leuven (Annouschka Laenen).
Lawrence BonneDepartment of Radiology, University Hospitals KU Leuven (Quinten Verhalleman, Lawrence Bonne, Eveline Claus, Jo Peluso, Geert Maleux).
Eveline ClausDepartment of Radiology, University Hospitals KU Leuven (Quinten Verhalleman, Lawrence Bonne, Eveline Claus, Jo Peluso, Geert Maleux).
Jo PelusoDepartment of Radiology, University Hospitals KU Leuven (Quinten Verhalleman, Lawrence Bonne, Eveline Claus, Jo Peluso, Geert Maleux).
Alexander WilmerMedical Intensive Care Unit, University Hospitals KU Leuven (Alexander Wilmer), Leuven, Belgium.
Geert MaleuxDepartment of Radiology, University Hospitals KU Leuven (Quinten Verhalleman, Lawrence Bonne, Eveline Claus, Jo Peluso, Geert Maleux).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study evaluated the technical and clinical outcomes of transcatheter arterial embolization (TAE) in patients with acute small-bowel bleeding (SBB) and aimed to identify potential risk factors for early recurrent bleeding after TAE. Methods: Thirty-one patients with SBB managed with TAE between January 2006 and December 2021 were included. Technical and clinical success was defined as angiographic occlusion of the bleeding artery and disappearance of clinical or laboratory signs of persistent bleeding without major complications. Complications were classified according to the Society of Interventional Radiology's guidelines. Kaplan-Meier estimates assessed overall survival, and logistic regression models determined risk factors for clinical success and early rebleeding. Results: Technical and clinical success were achieved in 30/31 (97%) and 19 (61%), respectively. Early recurrent bleeding was present in 9 (29%) patients, and was treated by repeat embolization in 4 patients, conversion to surgery in 4, and comfort therapy in 1 patient. TAE-related small bowel ischemia requiring surgery was found in 2 (6.5%) patients. Thirty-day and in-hospital mortality were 19% (6/31) and 23% (7/31), respectively; overall 5-year estimated survival was 60%. Thrombocytopenia and elevated prothrombin time (PT)/activated partial thromboplastin time (aPTT) levels prior to TAE were identified as risk factors for clinical failure (P=0.0026 and P=0.027, respectively), and for residual or early recurrent bleeding (P<0.001 and P=0.01, respectively). Conclusions: TAE is safe and effective for managing severe SBB; however, early recurrent bleeding was found in nearly one third of patients. Thrombocytopenia and elevated PT/aPTT levels were risk factors for early recurrent bleeding.

Indexed as

angiographyembolizationGastrointestinal bleedingsmall bowel

Identifiers

PMID39238795
PMCPMC11372541

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.