Evidence map›Paper›PMID 39238547›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2024

Speech Motion Anomaly Detection via Cross-Modal Translation of 4D Motion Fields from Tagged MRI.

Xiaofeng Liu, Fangxu Xing, Jiachen Zhuo, Maureen Stone, Jerry L Prince, Georges El Fakhri, Jonghye Woo

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Xiaofeng LiuGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114 USA.
Fangxu XingGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114 USA.
Jiachen ZhuoDept. of Radiology, University of Maryland School of Medicine, Baltimore, MD 21201 USA.
Maureen StoneDept. of Neural and Pain Sciences, University of Maryland School of Dentistry, Baltimore, MD 21201 USA.
Jerry L PrinceDept. of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD 21218 USA.
Georges El FakhriDept. of Radiology and Biomedical Imaging, Yale University, New Heaven, CT 06519, USA.
Jonghye WooGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114 USA.

Funding

A holistic approach to identifying functional units of tongue motion during speechR01DC018511 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI WOO, JONGHYE · 2020 to 2024
$2.6M
Predictors of Speech Quality after Tongue Cancer SurgeryR01CA133015 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI STONE, MAUREEN · 2009 to 2013
$2.5M
Tongue muscle function after cancer surgery using 4D MRI, DTI, and MR taggingR01DC014717 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI PRINCE, JERRY L · 2015 to 2019
$1.7M
NCI NIH HHS R01 CA133015NIDCD NIH HHS R01 DC014717NIDCD NIH HHS R01 DC018511
6 · The paper itself

Abstract

Understanding the relationship between tongue motion patterns during speech and their resulting speech acoustic outcomes-i.e., articulatory-acoustic relation-is of great importance in assessing speech quality and developing innovative treatment and rehabilitative strategies. This is especially important when evaluating and detecting abnormal articulatory features in patients with speech-related disorders. In this work, we aim to develop a framework for detecting speech motion anomalies in conjunction with their corresponding speech acoustics. This is achieved through the use of a deep cross-modal translator trained on data from healthy individuals only, which bridges the gap between 4D motion fields obtained from tagged MRI and 2D spectrograms derived from speech acoustic data. The trained translator is used as an anomaly detector, by measuring the spectrogram reconstruction quality on healthy individuals or patients. In particular, the cross-modal translator is likely to yield limited generalization capabilities on patient data, which includes unseen out-of-distribution patterns and demonstrates subpar performance, when compared with healthy individuals. A one-class SVM is then used to distinguish the spectrograms of healthy individuals from those of patients. To validate our framework, we collected a total of 39 paired tagged MRI and speech waveforms, consisting of data from 36 healthy individuals and 3 tongue cancer patients. We used both 3D convolutional and transformer-based deep translation models, training them on the healthy training set and then applying them to both the healthy and patient testing sets. Our framework demonstrates a capability to detect abnormal patient data, thereby illustrating its potential in enhancing the understanding of the articulatory-acoustic relation for both healthy individuals and patients.

Indexed as

Anomaly DetectionMotion FieldsSpeech SynthesisTagged MRI

Identifiers

PMID39238547
PMCPMC11377028

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.