Evidence map›Paper›PMID 39238523›Full record

ArticleInterventional pain medicine2022

Intra-flexor retinaculum steroid injection in elderly patients with carpal tunnel syndrome: A randomized clinical trial.

Reza S Roghani, Sam Kara, Mohammad J Taheri, Faeze Gohari, Sara Sadrneshin, Hein Linn Thant, Jose J Diaz, Johan Lokk

Abstract read
In one paragraph

Article in Interventional pain medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Reza S RoghaniDepartment of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden.
Sam KaraDepartment of Neurology, Larkin University & Health System, Miami, FL, USA.
Mohammad J TaheriDepartment of PM&R, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Faeze GohariDepartment of PM&R, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sara SadrneshinDepartment of PM&R, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hein Linn ThantDepartment of Physical Medicine and Rehabilitation, Larkin University & Health System, Miami, FL, USA.
Jose J DiazDepartment of Physical Medicine and Rehabilitation, Larkin University & Health System, Miami, FL, USA.
Johan LokkDepartment of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The efficacy of ultrasonography-guided intra-flexor retinaculum corticosteroid injection is compared to within-carpal tunnel steroid injection, for the treatment of elderly patients with carpal tunnel syndrome (CTS). Material & methods: In this prospective, double-blind, randomized trial, the elderly patients with CTS are allocated 1:1 into the two treatment groups. Subjects and assessors remained blinded to group allocation throughout the trial. All patients received 40 ​mg triamcinolone (1 ​mL) plus 1 ​mL of 2% lidocaine, either fenestrated in the flexor retinaculum (group 1) or injected within the carpal tunnel between the flexor retinaculum and median nerve (group 2). Patients were instructed to use a wrist splint for two weeks post-treatment. Symptom severity, grip, electrodiagnostic indices, and ultrasonographic features were measured at baseline and 6-weeks thereafter. The primary outcomes were median nerve distal motor and sensory latencies, and those secondary outcomes were Boston Carpal Tunnel Questionnaire (BCTQ) scores, visual analog scale (VAS) pain scores, and the median nerve inlet cross-sectional area (CSA). Results: Of 92 individuals screened, 50 eligible participants were randomized, all of whom completed the study and were included in the analysis. Patients receiving the intra-flexor retinaculum injection demonstrated significantly greater improvements in their total BCTQ score (p ​= ​0.023), VAS score (p ​= ​0.026), and inlet CSA (p ​= ​0.004), while the electrodiagnostic indices and the grip scale did not differ between groups. Conclusion: The intra-flexor retinaculum corticosteroid injection can provide better functional recovery and symptom reduction for elderly patients with CTS, compared to the within-carpal tunnel corticosteroid injection.

Indexed as

AgedCarpal tunel syndromeInjectionPainSteroidsSurgeryUltrasonographyWrist

Identifiers

PMID39238523
PMCPMC11372893

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.