Evidence map›Paper›PMID 39238511›Full record

ArticleInterventional pain medicine2022

Encephalopathy after unintentional intrathecal gadolinium: A letter to the editor.

Maxim Moradian, Gene Tekmyster, Jason J Wei, Henry Avetisian, Jayant N Acharya, Michael B Furman

Erratum issuedAbstract readLetter
In one paragraph

Article in Interventional pain medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Maxim MoradianInterventional Spine and Orthopedic Regenerative Experts, PC (iSCORE). California Sports and Spine Institute, PC (CSSI), 51 N. 5 Ave, Suite 301, Arcadia, CA, 91006, USA.
Gene TekmysterAssistant Professor of Clinical Orthopaedic Surgery, Keck Medicine of USC, Toyota Sports Performance Center, 555 N. Nash Street, El Segundo, CA, USA.
Jason J WeiUCLA Spine Center, 1131 Wilshire Blvd, Suite 100, Santa Monica, CA, 90401, USA.
Henry AvetisianInterventional Spine and Orthopedic Regenerative Experts, PC (iSCORE). California Sports and Spine Institute, PC (CSSI), 51 N. 5 Ave, Suite 301, Arcadia, CA, 91006, USA.
Jayant N AcharyaDepartment of Neurology, EC037. Penn State Hershey Medical Center, 30 Hope Drive, Hershey, PA, 17033, USA.
Michael B FurmanOSS Health, 1855 Powder Mill Road, York, PA, 17402, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Raise awareness of gadolinium encephalopathy, a rare cause of neurological symptoms. Setting: An L5-S1 interlaminar epidural steroid injection (IL-ESI) was performed with a gadolinium-based contrast agent (GBCA) due to the patient's history of allergic reaction to iodine-based contrast agents. Discussion: Several hours after administration of GBCA, the patient had nausea and vomiting with altered mental status. Patient was treated with dexamethasone IV, and was discharged on day 2. Patient had no residual deficits at follow-up two weeks later. Current literature shows that caution should be used to prevent inadvertent intrathecal GBCA, and doses >2.0 mmols are associated with serious adverse effects, including death. Conclusions: Intrathecal administration of GBCAs should be limited to less than 0.5 mmol. If adverse effects are experienced, IV steroids should be administered as soon as possible, and a CSF drain should be considered.

Identifiers

PMID39238511
PMCPMC11373013

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.