Evidence map›Paper›PMID 39238436›Full record

ArticleThe Journal of international medical research2024

Antibiotic prescription patterns in the emergency department of a tertiary healthcare center in Nepal: a descriptive cross-sectional study.

Samjhana Basnet, Pramesh Koju, Prabhat Silwal, Aashish Karki, Sumina Mainali, Prakash Sapkota, Surendra Kumar Madhup, Sanu Krishna Shrestha

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Article in The Journal of international medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Samjhana BasnetDepartment of General Practice and Emergency Medicine, Dhulikhel Hospital, Kathmandu University School of Medical Sciences, Kavrepalanchowk, Nepal.
Pramesh KojuDhulikhel Hospital, Kathmandu University School of Medical Sciences, Kavrepalanchowk, Nepal.
Prabhat SilwalDhulikhel Hospital, Kathmandu University School of Medical Sciences, Kavrepalanchowk, Nepal.ORCID 0000-0002-6873-7979
Aashish KarkiDhulikhel Hospital, Kathmandu University School of Medical Sciences, Kavrepalanchowk, Nepal.
Sumina MainaliDhulikhel Hospital, Kathmandu University School of Medical Sciences, Kavrepalanchowk, Nepal.
Prakash SapkotaDepartment of Internal Medicine, Dhulikhel Hospital, Kathmandu University School of Medical Sciences, Kavrepalanchowk, Nepal.
Surendra Kumar MadhupDepartment of Microbiology, Dhulikhel Hospital, Kathmandu University School of Medical Sciences, Kavrepalanchowk, Nepal.
Sanu Krishna ShresthaDepartment of General Practice and Emergency Medicine, Dhulikhel Hospital, Kathmandu University School of Medical Sciences, Kavrepalanchowk, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe antibiotic prescription patterns in the emergency department (ED) of a tertiary healthcare center in Nepal.

methodsThis was a descriptive cross-sectional study of hospital records of patients who visited the ED.

resultsOf the 758 ED patients included in the study, 384 (50.6%) received a total of 536 antibiotic prescriptions. Common indications for antibiotic prescriptions included respiratory infection (37.5%), gastrointestinal infection (19.3%), urinary infection (10.4%), and prophylaxis (29.9%). Antibiotics listed as essential in the National List of Essential Medicines (NLEM) and generic formulations were used in 77.1% and 61.9% of the antibiotic prescriptions, respectively. Injectable antibiotics were prescribed to 54.9% of the 384 patients. Frequently prescribed antibiotics included ceftriaxone (34.1%), metronidazole (18.5%), amoxicillin + clavulanic acid (15.9%), and cefixime (14.3%). Bacterial culture testing was performed in 15.1% of the patients who received antibiotics.

conclusionsThis study showed that overuse of antibiotics, prescription of branded antibiotics, prescription of antibiotics not listed in the NLEM, prophylactic use of antibiotics, and empirical treatment of suspected infections without isolation of pathogens were all prevalent. We recommend more research to determine the causes underlying these practices and develop interventions to limit such practices.

Indexed as

Anti-Bacterial AgentsEmergency Service, HospitalTertiary Care CentersAdolescentAdultAgedCefiximeCeftriaxoneChildChild, PreschoolCross-Sectional StudiesDrug PrescriptionsFemaleHumansMaleMetronidazoleAnti-Bacterial AgentsCefiximeCeftriaxoneMetronidazoleAntibacterial agentantibioticcross-sectional studyemergency departmenthospital recordinfectious diseaseprescription pattern

Identifiers

PMID39238436
PMCPMC11378181

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.