Evidence map›Paper›PMID 39237929›Full record

ArticleBMC psychiatry2024

Sex differences in physiological correlates of affectively driven decision-making behavior in adult ADHD.

Eva Halbe, Alina Sophie Heger, Fabian Kolf, Philippa Hüpen, Moritz Bergmann, Ben J Harrison, Christopher G Davey, Alexandra Philipsen, Silke Lux

Abstract read
In one paragraph

Article in BMC psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eva HalbeDepartment of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany. eva_halbe@web.de.
Alina Sophie HegerDepartment of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
Fabian KolfDepartment of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
Philippa HüpenDepartment of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Moritz BergmannDepartment of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
Ben J HarrisonDepartment of Psychiatry, The University of Melbourne, Melbourne, VIC, Australia.
Christopher G DaveyDepartment of Psychiatry, The University of Melbourne, Melbourne, VIC, Australia.
Alexandra Philipsen *Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
Silke Lux *Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSex differences in the symptomatology of adults with attention-deficit/hyperactivity disorder (ADHD) have often been overlooked when studying behavioral abnormalities. However, it is known that women exhibit considerably more stronger symptoms related to emotional competence than men. Since affective functions significantly influence the processing of risky decision-making and risk-engagement, we assume that risky behavior in ADHD is affected by sex differences. Therefore, we specifically investigated sex-specific effects on the interaction between emotionally induced changes in physiology and behavioral performance on a decision-making task.

methodsSkin conductance responses of twenty-nine adults with ADHD (n = 16 male; n = 13 female) and thirty-three adults in the control group (n = 14 male; n = 19 female) were recorded during the performance in a modified version of the Balloon Analogue Risk Task (BART). Additional questionnaires were used to reveal insights in the self-assessment of emotional competence, risk perception, and feedback sensitivity. Emotional arousal and decision-making behavior were analyzed using linear mixed-effects models.

resultsResults showed different effects of sex on risk behaviors in controls and ADHD. In contrast to healthy controls, female adults with ADHD showed a significantly greater risk engagement in the BART compared to males with ADHD. This contrary sex relation was not observed in skin conductance responses and revealed a significantly different sex-dependent correlation of body response and behavioral task performance in ADHD. Comparisons with results from self-assessments furthermore indicate a reduced behavioral self-perception in women with ADHD, but not in men.

conclusionIn summary, we found an altered interaction between physiological activity and risky behavior in women with ADHD. Thus, the present study indicates a reduced sensitivity towards the own bodily responses in women with ADHD, which could consequently cause increased risky DM behavior in daily life. The current results suggest that more consideration needs to be given to sex-specific effects on physiological processes and behavior in adults with ADHD.

Indexed as

Attention Deficit Disorder with HyperactivityDecision MakingGalvanic Skin ResponseRisk-TakingAdultEmotionsFemaleHumansMaleSex CharacteristicsSex FactorsYoung AdultAffective functionAttention-deficit/hyperactivity disorderAutonomic nervous systemBalloon analogue risk taskPhysiological measurementRisky decision-making behaviorSex differencesSkin conductance response

Identifiers

PMID39237929
PMCPMC11375934

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.