Evidence map›Paper›PMID 39237872›Full record

ArticleBMC neurology2024

Spinal cord compression by cystic IgG4-related spinal pachymeningitis mimicking neurocysticercosis: a case report.

David Augusto Batista Sá Araújo, Rodrigo Mariano Ribeiro, Pedro Lucas Grangeiro Sá Barreto Lima, Dánton Campos de Queiroz, Milena Sales Pitombeira, Bernardo Martins, Pablo Picasso Araújo Coimbra, Cleto Dantas Nogueira, Pedro Braga-Neto, Guilherme Diogo Silva and 1 more

Abstract readCase Reports
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Article in BMC neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

David Augusto Batista Sá AraújoFaculty of Medicine, Federal University of Ceara, Alexandre Baraúna St., 949, Fortaleza, 60430-160, Ceara, Brazil.
Rodrigo Mariano RibeiroFaculty of Medicine, Federal University of Ceara, Alexandre Baraúna St., 949, Fortaleza, 60430-160, Ceara, Brazil.
Pedro Lucas Grangeiro Sá Barreto LimaFaculty of Medicine, Federal University of Ceara, Alexandre Baraúna St., 949, Fortaleza, 60430-160, Ceara, Brazil.
Dánton Campos de QueirozFaculty of Medicine, Federal University of Ceara, Alexandre Baraúna St., 949, Fortaleza, 60430-160, Ceara, Brazil.
Milena Sales PitombeiraDepartment of Neurology, General Hospital of Fortaleza, Ávila Goularte St., 900, Fortaleza, 60150-160, Ceara, Brazil.
Bernardo MartinsRede SARAH de Hospitais de Reabilitação, SMHS - Área Especial, Qd 501, Asa Sul, Brasilia, Distrito Federal, Brazil.
Pablo Picasso Araújo CoimbraDepartment of Neurology, General Hospital of Fortaleza, Ávila Goularte St., 900, Fortaleza, 60150-160, Ceara, Brazil.
Cleto Dantas NogueiraLaboratório Argos, Santos Dumont Ave., 5753, Fortaleza, 60175-047, Ceara, Brazil.
Pedro Braga-NetoDivision of Neurology, Department of Clinical Medicine, Federal University of Ceara, Prof. Costa Mendes St., 1608, 4th Floor, Fortaleza, 60430-140, Ceara, Brazil.
Guilherme Diogo SilvaDepartment of Neurology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Dr. Ovídio Pires de Campos St., 225, São Paulo, São Paulo, Brazil.
Paulo Ribeiro NóbregaDivision of Neurology, Department of Clinical Medicine, Federal University of Ceara, Prof. Costa Mendes St., 1608, 4th Floor, Fortaleza, 60430-140, Ceara, Brazil. paulo_r_med@yahoo.com.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo report a case of IgG4-related pachymeningitis presenting with cystic lesions mimicking neurocysticercosis. CASE PRESENTATION: A 40-year-old female patient with tetraparesis, dysphagia and dysphonia was evaluated with clinical examination, magnetic resonance imaging, and meningeal biopsy. Magnetic resonance imaging (MRI) revealed diffuse pachymeningeal enhancement involving the cranial, cervical, thoracic, and lumbar segments with spinal cord compression and cystic lesions. CSF immunology was initially positive for cysticercus cellulosae. After disease progression a meningeal biopsy was compatible with IgG4 related disease. The patient had partial response to rituximab and needed multiple surgical procedures for spinal cord decompression and CSF shunting.

conclusionsThis case highlights the possibility of IgG4-related disease in patients with diffuse pachymeningitis causing spinal cord compression, even with cystic lesions on MRI. Diagnosis of IgG4-related pachymeningitis is paramount due to the possibility of treatment response to immunotherapy, particularly to anti-CD20 agents.

Indexed as

Immunoglobulin G4-Related DiseaseMeningitisNeurocysticercosisSpinal Cord CompressionAdultDiagnosis, DifferentialFemaleHumansImmunoglobulin GMagnetic Resonance ImagingImmunoglobulin GImmunoglobulin G4-related diseaseNeurocysticercosisNeuroimmunologyPachymeningitisSpinal cord

Identifiers

PMID39237872
PMCPMC11375994

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.