Evidence map›Paper›PMID 39237865›Full record

ArticleBMC cardiovascular disorders2024

Coronary thrombosis and myocardial ischemia in Kawasaki disease: a case report.

Lichao Gao, Chunhong Xie, Qing Zhang, Xiaofeng Wang, Songling Fu, Jian Hu, Yiying Zhang, Fangqi Gong

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Lichao Gao *Department of Cardiology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, 57 Zhugan Lane, 310003, Hangzhou, Zhejiang, P. R. China.
Chunhong Xie *Department of Cardiology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, 57 Zhugan Lane, 310003, Hangzhou, Zhejiang, P. R. China.
Qing ZhangDepartment of Cardiology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, 57 Zhugan Lane, 310003, Hangzhou, Zhejiang, P. R. China.
Xiaofeng WangDepartment of IT Center, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, P. R. China.
Songling FuDepartment of Cardiology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, 57 Zhugan Lane, 310003, Hangzhou, Zhejiang, P. R. China.
Jian HuDepartment of Cardiology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, 57 Zhugan Lane, 310003, Hangzhou, Zhejiang, P. R. China.
Yiying ZhangDepartment of Cardiology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, 57 Zhugan Lane, 310003, Hangzhou, Zhejiang, P. R. China.
Fangqi GongDepartment of Cardiology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, 57 Zhugan Lane, 310003, Hangzhou, Zhejiang, P. R. China. gongfangqi@zju.edu.cn.

Funding

National Natural Science Foundation of China 81970434
6 · The paper itself

Abstract

backgroundCoronary artery thrombosis and myocardial ischemia caused by giant coronary aneurysms are the main causes of death in children with Kawasaki disease. The use of thrombolytic therapy in children with Kawasaki disease who have coronary thrombosis is a controversial topic, especially with respect to the timing of treatment. CASE PRESENTATION: In this article, we report a case of a child aged two years and nine months with Kawasaki disease whose coronary arteries had no involvement in the acute phase. However, by only one week after discharge, the patient returned because we found giant coronary aneurysms complicated by thrombosis via echocardiography. Despite aggressive thrombolytic therapy, the child developed myocardial ischemia during thrombolytic therapy. Fortunately, because of timely treatment, the child's thrombus has dissolved, and the myocardial ischemia has resolved.

conclusionsThis case suggests that for patients at high risk of coronary artery aneurysms, echocardiography may need to be reviewed earlier. Low-molecular-weight heparin should be added to antagonize the early procoagulant effects of warfarin when warfarin therapy is initiated. In the case of first-detected coronary thrombosis, aggressive thrombolytic therapy may be justified, particularly during the acute and subacute phases of the disease course.

Indexed as

Coronary AneurysmCoronary ThrombosisMucocutaneous Lymph Node SyndromeMyocardial IschemiaThrombolytic TherapyAnticoagulantsChild, PreschoolCoronary AngiographyFibrinolytic AgentsHumansMaleTreatment OutcomeAnticoagulantsFibrinolytic AgentsCase reportCoronary artery aneurysmsCoronary artery thrombosisKawasaki diseaseMyocardial ischemia

Identifiers

PMID39237865
PMCPMC11375974

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.