Evidence map›Paper›PMID 39237746›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

Efficient α and β

Hannelore Ceuppens, Ana Rita Pombo Antunes, Laurent Navarro, Thomas Ertveldt, Marion Berdal, Surasa Nagachinta, Kirsten De Ridder, Tony Lahoutte, Marleen Keyaerts, Nick Devoogdt and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hannelore Ceuppens *Vrije Universiteit Brussel, Department of Biomedical Sciences, Translational Oncology Research Center, Laboratory for Molecular and Cellular Therapy, Laarbeeklaan 103. Building E, Brussels, 1090, Belgium. Hannelore.Ceuppens@vub.be.ORCID 0000-0003-0187-4204
Ana Rita Pombo Antunes *Precirix NV/SA, Burg. Etienne Demunterlaan 3, Brussels, B-1090, Belgium.
Laurent NavarroPrecirix NV/SA, Burg. Etienne Demunterlaan 3, Brussels, B-1090, Belgium.
Thomas ErtveldtVrije Universiteit Brussel, Molecular Imaging and Therapy Research Group, Laarbeeklaan 103/K, Brussels, 1090, Belgium.
Marion BerdalPrecirix NV/SA, Burg. Etienne Demunterlaan 3, Brussels, B-1090, Belgium.
Surasa NagachintaPrecirix NV/SA, Burg. Etienne Demunterlaan 3, Brussels, B-1090, Belgium.
Kirsten De RidderVrije Universiteit Brussel, Department of Biomedical Sciences, Translational Oncology Research Center, Laboratory for Molecular and Cellular Therapy, Laarbeeklaan 103. Building E, Brussels, 1090, Belgium.
Tony LahoutteVrije Universiteit Brussel, Molecular Imaging and Therapy Research Group, Laarbeeklaan 103/K, Brussels, 1090, Belgium.
Marleen KeyaertsVrije Universiteit Brussel, Molecular Imaging and Therapy Research Group, Laarbeeklaan 103/K, Brussels, 1090, Belgium.
Nick DevoogdtVrije Universiteit Brussel, Molecular Imaging and Therapy Research Group, Laarbeeklaan 103/K, Brussels, 1090, Belgium.
Cleo GoyvaertsVrije Universiteit Brussel, Molecular Imaging and Therapy Research Group, Laarbeeklaan 103/K, Brussels, 1090, Belgium.
Matthias D'Huyvetter *Precirix NV/SA, Burg. Etienne Demunterlaan 3, Brussels, B-1090, Belgium. Matthias.Dhuyvetter@precirix.com.
Karine Breckpot *Vrije Universiteit Brussel, Department of Biomedical Sciences, Translational Oncology Research Center, Laboratory for Molecular and Cellular Therapy, Laarbeeklaan 103. Building E, Brussels, 1090, Belgium. Karine.Breckpot@vub.be.

Funding

Bijzonder Onderzoeksfonds UGent iBOF/23/043Eutopia Foundation OZR3808BOFFonds Wetenschappelijk Onderzoek 12H3619NFonds Wetenschappelijk Onderzoek 1801619NFonds Wetenschappelijk Onderzoek 1S06622NInnoviris BRGRD44Kom op tegen Kanker ANI304Kom op tegen Kanker ANI368Stichting Wetenschappelijk Onderzoek Oogziekenhuis G041721NVrije Universiteit Brussel SRP48
6 · The paper itself

Abstract

purposeTargeted radionuclide therapy (TRT) is a cancer treatment with relative therapeutic efficacy across various cancer types. We studied the therapeutic potential of TRT using fibroblast activation protein-α (FAP) targeting sdAbs (4AH29) labelled with

methodsWe studied the biodistribution and tumour uptake of [

resultsThe biodistribution showed high tumour uptake of [

conclusion[

Indexed as

Alpha ParticlesGelatinasesMembrane ProteinsSerine EndopeptidasesActiniumAnimalsCell Line, TumorDisease Models, AnimalEndopeptidasesFemaleFibroblast Activation Protein AlphaHumansIodine RadioisotopesMiceTissue DistributionActiniumActinium-225EndopeptidasesFibroblast Activation Protein AlphaGelatinasesIodine RadioisotopesMembrane ProteinsSerine EndopeptidasesFibroblast activation protein-αProgrammed death-ligand 1Single domain antibodiesTargeted radionuclide therapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.