ArticleCommunications medicine2024
The influence of socioeconomic status on individual attitudes and experience with clinical trials.
Article in Communications medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Strategies to increase participant diversity in pediatric research: a systematic review.Pediatric research · 2026Pooled it
- Demographic Composition of Participants in Sex Chromosome Aneuploidy Studies Across the Globe: A 20-Year Systematic Review.American journal of medical genetics. Part A · 2026Pooled it
- Effect of opt-in versus opt-out framing on trial recruitment: a study within a trial of the GAMEPAD randomized trial.American heart journal · 2026Trial
- Randomized Comparison of Online Motivational Themes in Clinical Trial Recruitment.Circulation. Cardiovascular quality and outcomes · 2025Trial
- Access to translated invitations online increases involvement of linguistically diverse households in a population-based study: a cluster randomized controlled study.Scientific reports · 2025Trial
- Parental motivations, facilitators, and barriers to participating in a pediatric vaccine trial in Kathmandu, Nepal: A qualitative study.Human vaccines & immunotherapeutics · 2026Article
- Associations of parental physical activity and physical fitness with motor competence, physical fitness, anthropometry, and 24-hour movement behaviors in preschool children: A cross-sectional study.Journal of exercise science and fitness · 2026Article
- Patient and Caregiver Reported Barriers to Cancer Clinical Trial Participation: A Scoping Review.Cancer reports (Hoboken, N.J.) · 2026Article
- Remote Recruitment to Diversify Infant Research Participation: Lessons From the Infant Vaccine Biepository.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- A community-based qualitative study of perspectives on alcohol public health interventions and experiences of alcohol use.BMC public health · 2026Article
- Vulnerability, protection and fairness: ethical and regulatory limits in small-N gene therapy trials.Trials · 2026Article
- Theoretical and practical challenges for capturing reserve and resilience in aging and Alzheimer's disease: A narrative review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Drivers of Research Participation Among Racially and Ethnically Underrepresented Women: Insights from Semi-Structured Interviews.Journal of racial and ethnic health disparities · 2026Article
- The ethical permissibility of financial incentives.Medicine, health care, and philosophy · 2026Article
- Article
- Attitudes and Willingness to Participate in Drug Clinical Trials Among Patients With Cancer: Multistage Qualitative Study.Journal of medical Internet research · 2026Article
- Article
- Group-Based Medical Mistrust and Logistical Factors Influencing Rheumatology Clinical Trial Enrollment: A Single-Center Cross-Sectional Survey.ACR open rheumatology · 2026Article
- Guide on Selection of Optimal Motivational Themes for Use in a Clinical Trial Recruiting Black US Adults: Survey Study.Journal of medical Internet research · 2026Article
- How exclusion criteria can hinder eligibility for lung cancer studies among different racial and ethnic groups.PLOS digital health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCharacterizing perceptions of clinical trials among the socioeconomically disadvantaged is necessary for understanding how social determinants of health such as socioeconomic disparities in education and income can affect people's awareness of and exposure to clinical trials
methodsA survey was distributed in spring 2023 among a survey taking sample stratified by demographic variables to reflect the U.S. POPULATION: The survey assessed the socioeconomic status of the respondent and related covariates, as well as outcome measures including interest in joining a clinical trial, concerns relating to participation, and whether the respondent had previously been asked to participate. Multiple and logistic regression were used to assess the relationship between predictor and outcome variables
resultsHere we show the results of outcome measures regressed on main predictors related to socioeconomic status and related demographic predictors. Education, employment status, insurance coverage, and English proficiency were significant predictors of interest in clinical trial participation. Education and the presence of a healthcare professional or former clinical trial participant in the respondent's personal network were significant predictors of whether the respondent had previously been asked to participate in a clinical trial
conclusionsThe results of the analysis reveal how socioeconomically vulnerable groups, including those from low income and low education groups, are being excluded in clinical research. Analyses also uncovered the impact of clinical trial social influence-the presence of having a family or friend in one's social network who participated in a clinical trial-on willingness to participate and exposure to clinical trials.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.