Evidence map›Paper›PMID 39237564›Full record

ArticleNature communications2024

Unveiling the solution structure of a DNA duplex with continuous silver-modified Watson-Crick base pairs.

Uroš Javornik, Antonio Pérez-Romero, Carmen López-Chamorro, Rachelle M Smith, José A Dobado, Oscar Palacios, Mrinal K Bera, May Nyman, Janez Plavec, Miguel A Galindo

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Determination of silver(I)-binding sites in canonical B-DNA by NMR spectroscopy.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Uroš Javornik *Slovenian NMR Center, National Institute of Chemistry, SI-1000, Ljubljana, Slovenia.ORCID 0000-0002-7959-6681
Antonio Pérez-Romero *Departamento de Química Inorgánica, Universidad de Granada, 18001, Granada, Spain.
Carmen López-ChamorroDepartamento de Química Inorgánica, Universidad de Granada, 18001, Granada, Spain.
Rachelle M SmithDepartment of Chemistry, Oregon State University, Corvallis, OR, 97331-4003, USA.
José A DobadoDepartamento de Química Orgánica, Universidad de Granada, 18001, Granada, Spain.ORCID 0000-0001-7714-1715
Oscar PalaciosDepartament de Química, Universitat Autònoma de Barcelona, 08193, Cerdanyola del Vallès, Barcelona, Spain.ORCID 0000-0002-2987-7303
Mrinal K BeraNSF's ChemMatCARS, Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, 60637, USA.
May NymanDepartment of Chemistry, Oregon State University, Corvallis, OR, 97331-4003, USA. may.nyman@oregonstate.edu.ORCID 0000-0002-1787-0518
Janez PlavecSlovenian NMR Center, National Institute of Chemistry, SI-1000, Ljubljana, Slovenia. janez.plavec@ki.si.ORCID 0000-0003-1570-8602
Miguel A GalindoDepartamento de Química Inorgánica, Universidad de Granada, 18001, Granada, Spain. magalindo@ugr.es.ORCID 0000-0003-4355-4313

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The challenge of transforming organized DNA structures into their metallized counterparts persists in the scientific field. In this context, utilizing DNA molecules modified with 7-deazapurine, provides a transformative solution. In this study, we present the solution structure of a DNA duplex that can be transformed into its metallized equivalent while retaining the natural base pairing arrangement through the creation of silver-modified Watson-Crick base pairs. Unlike previously documented X-ray structures, our research demonstrates the feasibility of preserving the intrinsic DNA self-assembly while incorporating Ag

Indexed as

Base PairingDNANucleic Acid ConformationSilverModels, MolecularSolutionsDNASilverSolutions

Identifiers

PMID39237564
PMCPMC11377744

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.