Evidence map›Paper›PMID 39237398›Full record

SynthesisInternational dental journal2025

Comparison of Microbiota in Zirconia and Titanium Implants: A Qualitative Systematic Review.

Majid Bonyadi Manesh, Neda Vatankhah, Fatemeh Bonyadi Manesh

Abstract readSystematic ReviewComparative Study
In one paragraph

Synthesis in International dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Majid Bonyadi ManeshDepartment of Oral and Maxillofacial Prosthodontics, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
Neda VatankhahDepartment of Pharmaceutical, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: vatankhahn92@gmail.com.
Fatemeh Bonyadi ManeshDepartment of Restorative Dentistry and Endodontics, School of Dentistry, North Khorasan University of Medical Sciences, Bojnord, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this systematic review, we examine the variations in microbiota on zirconia versus titanium implants, providing insights into their impact on dental health and outcomes. The ongoing discussion regarding whether to use zirconia or titanium for implants underscores the significance of microbiota colonization in determining the longevity and performance of implants.

methodsResearch questions were formulated following the Participants, Intervention, Comparison, and Outcomes framework, and a PROSPERO protocol was registered. A thorough systematic search was carried out in PubMed, Embase, and Web of Science. Two reviewers independently assessed the reports against the Participants, Intervention, Comparison, and Outcomes criteria, including the inclusion and exclusion criteria. Risk of bias was assessed using the Quality Assessment Tool for In Vitro Studies (QUIN Tool).

resultsOf the 2063 articles identified, 19 articles fulfilled the inclusion criteria and subjected to quality assessment. All of the included studies were in vitro research with low (31.5%) or moderate (36.8%) or high (31.5%) risk of bias and reported data from 2 implant abutments. Zirconia implants displayed a higher occurrence of Gram-negative bacteria, such as Tannerella, Aggregatibacter, and Porphyromonas. In contrast, titanium implants showed a greater prevalence of Gram-positive bacteria, including Streptococcus, Lactobacillus acidophilus, and Staphylococcus species.

conclusionAccording to the findings of the current study, both zirconia and titanium implants support the growth of different microorganisms. There were also differences in the quakity and the quantity of microorganisms detected on each material. These differences in microbial profiles indicate that the selection of implant material might impact the microbial ecosystem on the implant surface, potentially affecting clinical outcomes such as infection rates and the longevity of the implant.

Indexed as

Dental ImplantsMicrobiotaTitaniumZirconiumHumansDental ImplantsTitaniumZirconiumzirconium oxideMicrobiotaSystematic reviewTitaniumZirconia

Identifiers

PMID39237398
PMCPMC11806319

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.