Evidence map›Paper›PMID 39237118›Full record

ArticleBrain pathology (Zurich, Switzerland)2025

Lack of classical astroblastoma features in pediatric MN1::BEND2-fused brain tumors.

Nicholas Chapman, Mohammed Iqbal, Adam D Walker, Debra Hawes, Tom Belle Davidson, Nathan Robison, Benita Tamrazi, Jianling Ji, Mark D Krieger, Jennifer A Cotter

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain pathology (Zurich, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nicholas ChapmanDepartment of Surgery and Division of Neurosurgery, Children's Hospital Los Angeles, Los Angeles, California, USA.ORCID 0000-0001-8014-8440
Mohammed IqbalDepartment of Neurosurgery, University of Texas, Dell Medical School, Austin, Texas, USA.
Adam D WalkerDepartment of Pathology & Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.
Debra HawesDepartment of Pathology & Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.
Tom Belle DavidsonKeck School of Medicine, University of Southern California, Los Angeles, California, United States.
Nathan RobisonKeck School of Medicine, University of Southern California, Los Angeles, California, United States.
Benita TamraziKeck School of Medicine, University of Southern California, Los Angeles, California, United States.
Jianling JiDepartment of Pathology & Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.
Mark D KriegerDepartment of Surgery and Division of Neurosurgery, Children's Hospital Los Angeles, Los Angeles, California, USA.
Jennifer A CotterDepartment of Pathology & Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three distinct MN1::BEND2 fusion-positive tumors in pediatric patients. (A) Clinical course for each patient was variable in part due to differences in initial diagnosis. Each patient responded favorably to gross total resection and is stable at last follow-up. (B) Histologic diversity, lack of prominent classical astroblastoma features, and variable immunoexpression of key markers makes microscopic diagnosis challenging.

Indexed as

Brain NeoplasmsNeoplasms, NeuroepithelialChildChild, PreschoolFemaleHumansTrans-ActivatorsTumor Suppressor ProteinsMN1 protein, humanTrans-ActivatorsTumor Suppressor ProteinsastroblastomaependymomaMN1‐alteredMN1::BEND2 fusionpediatricRNA sequencing

Identifiers

PMID39237118
PMCPMC11835438

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.