Evidence map›Paper›PMID 39235361›Full record

ArticleEuropean journal of immunology2024

Innate T-cell-derived IL-17A/F protects from bleomycin-induced acute lung injury but not bleomycin or adenoviral TGF-β1-induced lung fibrosis in mice.

Marie T Moog, Melina Baltes, Tina Röpke, Franziska Aschenbrenner, Regina Maus, Jennifer Stolper, Danny Jonigk, Immo Prinz, Martin Kolb, Ulrich A Maus

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Systemic effects of oral tolerance improve the healing of several and concomitant wounds on different parts of the body.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marie T MoogDivision of Experimental Pneumology, Clinic for Pneumology, Hannover Medical School, Hannover, Germany.
Melina BaltesDivision of Experimental Pneumology, Clinic for Pneumology, Hannover Medical School, Hannover, Germany.
Tina RöpkeDivision of Experimental Pneumology, Clinic for Pneumology, Hannover Medical School, Hannover, Germany.
Franziska AschenbrennerDivision of Experimental Pneumology, Clinic for Pneumology, Hannover Medical School, Hannover, Germany.
Regina MausDivision of Experimental Pneumology, Clinic for Pneumology, Hannover Medical School, Hannover, Germany.
Jennifer StolperDivision of Experimental Pneumology, Clinic for Pneumology, Hannover Medical School, Hannover, Germany.
Danny JonigkInstitute of Pathology, RWTH University Medical Center, Aachen, Germany.
Immo PrinzInstitute of Systems Immunology, University Medical Center Hamburg-Eppendorf, Germany.
Martin KolbDepartment of Medicine, Pathology, and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Ulrich A MausDivision of Experimental Pneumology, Clinic for Pneumology, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-6172-8746

Funding

Federal Ministry of Education and ResearchGerman Center for Lung Research
6 · The paper itself

Abstract

The pathobiology of IL-17 in lung fibrogenesis is controversial. Here we examined the role of IL-17A/F in bleomycin (BLM) and adenoviral TGF-β1-induced lung fibrosis in mice. In both experimental models, WT and IL17af

Indexed as

Acute Lung InjuryBleomycinInterleukin-17Mice, KnockoutPulmonary FibrosisTransforming Growth Factor beta1AdenoviridaeAnimalsDisease Models, AnimalImmunity, InnateLungMiceMice, Inbred C57BLBleomycinIl17a protein, mouseIl17f protein, mouseInterleukin-17Transforming Growth Factor beta1FibrosisIL‐17InjuryLungTh17γδ T cells

Identifiers

PMID39235361
PMCPMC11628887

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.