Evidence map›Paper›PMID 39235251›Full record

ArticleAntimicrobial agents and chemotherapy2024

Incidence of serotonin syndrome in patients receiving tedizolid and concomitant serotonergic agents.

Yingsi Fang, Lloyd G Clarke, Brandon J Smith, Sunish Shah

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yingsi FangDepartment of Pharmacy, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.ORCID 0009-0004-7304-3543
Lloyd G ClarkeDepartment of Pharmacy, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Brandon J SmithAntibiotic Management Program, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Sunish ShahDepartment of Pharmacy, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-8873-1451

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the real-world incidence rate of serotonin syndrome in patients receiving tedizolid and concomitant serotonergic agents. A retrospective cohort of 479 adult patients was assessed between January 2015 and July 2023. Overall, a rare rate of 0.4% (2/479) of possible serotonin syndrome with tedizolid was identified. Given that concomitant serotonergic agents were commonly used, further study is warranted to determine causality.

Indexed as

Anti-Bacterial AgentsSerotonin SyndromeAdultAgedFemaleHumansIncidenceMaleMiddle AgedOxazolidinonesRetrospective StudiesSerotonin AgentsTetrazolesAnti-Bacterial AgentsOxazolidinonesSerotonin AgentstedizolidTetrazoleslinezolidserotonin syndrometedizolidthrombocytopenia

Identifiers

PMID39235251
PMCPMC11459941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.