Evidence map›Paper›PMID 39234948›Full record

Trial reportJournal of cosmetic dermatology2024

Controlled comparison evaluation of the soothing effect of 3 cosmetic products on skin discomfort induced by an irritant chemical agent (capsaicin).

Maria Vitale, Ana López, Maria Teresa Truchuelo, Vincenzo Nobile, Massimo Milani, María José Gómez-Sánchez

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Journal of cosmetic dermatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria VitaleMedical Affairs Department, Cantabria Labs, Madrid, Spain.
Ana LópezR&D Department, Cantabria Labs, Madrid, Spain.ORCID https://orcid.org/0000-0003-0859-3536
Maria Teresa TruchueloVithas Nuestra Señora de América Hospital, Madrid, Spain.ORCID https://orcid.org/0000-0002-9691-0476
Vincenzo NobileR&D Department, Complife Italia S.r.l., Pavia, Italy.ORCID https://orcid.org/0000-0001-9147-302X
Massimo MilaniMedical Department Cantabria Labs Difa Cooper, Varese, Italy.ORCID https://orcid.org/0000-0001-7559-1202
María José Gómez-SánchezMedical affairs Department, Cantabria Labs, Madrid, Spain.

Funding

cantabria labs
6 · The paper itself

Abstract

backgroundSensitive skin is a highly prevalent problem. The objective of the study was to assess whether the tested products are effective and safe in terms of improving the symptoms of sensitive skin.

methodsA clinical randomized split-face study was carried out on 24 healthy female subjects. Three cosmetic combinations were tested versus vehicle: product A (Solía Thermal Spring Water-TSW-from Cantabria, Spain + diatom algae-P. tricornutum-extract), product B (Solía TSW + diatom algae extract + Annona cherimola Fruit Extract) and product C (Solía TSW + diatom algae extract + Annona cherimola Fruit Extract + niacinamide). Prior to each application of the study Product (A, B, or C)/vehicle, 10% of aqueous solution of capsaicin to induce skin irritation was applied, mimicking the symptoms of sensitive skin. Stinging and burning sensations were evaluated at different time points.

resultsAll three tested products A, B, and C showed to act better in calming the symptoms induced by capsaicin when compared to the vehicle.

conclusionsThe tested products would be an interesting option for treating stinging and burning sensations in sensitive skin patients.

Indexed as

CapsaicinCosmeticsPlant ExtractsAdultAnnonaDermatitis, IrritantFemaleHealthy VolunteersHumansIrritantsMiddle AgedYoung AdultCapsaicinCosmeticsIrritantsPlant ExtractsAquammunistburningsensitive skinthermal spring waterTRPV1

Identifiers

PMID39234948
PMCPMC11626353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.