Evidence map›Paper›PMID 39234631›Full record

ArticleJournal of the International Association of Providers of AIDS Care

Provider Perspectives on Rapid Treatment Initiation Among People Newly Diagnosed With HIV: A New Message of "Urgency"?

Breana J Uhrig Castonguay, Noah Mancuso, Sarah Hatcher, Sable Watson, Eunice Okumu, Rica Abbott, Carol E Golin, Victoria Mobley, Erika Samoff, Heidi Swygard and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Breana J Uhrig CastonguayDepartment of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0001-6046-6353
Noah MancusoResearch Triangle Institute (RTI) International, Research Triangle Park, NC, USA.ORCID 0000-0002-4442-9293
Sarah HatcherDepartment of Medicine, Section on Infectious Diseases, Wake Forest University School of Medicine, Wake Forest, NC, USA.ORCID 0009-0003-9800-4789
Sable WatsonCenter for AIDS Research (CFAR), University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Eunice OkumuCenter for AIDS Research (CFAR), University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Rica AbbottDepartment of Medicine, Section on Infectious Diseases, Wake Forest University School of Medicine, Wake Forest, NC, USA.
Carol E GolinDepartment of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Victoria MobleyDivision of Public Health, Communicable Disease Branch, North Carolina Department of Health and Human Services, Chapel Hill, NC, USA.
Erika SamoffDivision of Public Health, Communicable Disease Branch, North Carolina Department of Health and Human Services, Chapel Hill, NC, USA.
Heidi SwygardDepartment of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Candice J McNeilDepartment of Medicine, Section on Infectious Diseases, Wake Forest University School of Medicine, Wake Forest, NC, USA.
Cynthia L GayDepartment of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Funding

Training Program in Approaches to Address Social-Structural Factors Related to HIV Intersectionally (TASHI)T32MH130247 · NIMH · GEORGE WASHINGTON UNIVERSITY · PI Ingrid Alisa Bowleg, Deanna L Kerrigan · 2022 to 2026
$965k
NIMH NIH HHS T32 MH130247
6 · The paper itself

Abstract

backgroundEarly initiation of antiretroviral therapy improves human immunodeficiency virus (HIV) outcomes. However, achieving earlier treatment initiation is challenging for many reasons including provider awareness and clinic barriers; this study sought to understand perceptions of an early initiation program.

methodsWe interviewed 10 providers from 3 HIV clinics in North Carolina (October-November 2020). We asked providers about overall perceptions of early initiation and the pilot program. We developed narrative summaries to understand individual contexts and conducted thematic analysis using NVivo.

resultsProviders believed earlier initiation would signal an "extra sense of urgency" about the importance of antiretroviral therapy-a message not currently reflected in standard of care. Safety was a consistent concern. Cited implementation barriers included transportation assistance, medication sustainability, and guidance to address increased staff time and appointment availability.

conclusionOur qualitative findings highlight the need for training on the safety of early initiation and addressing staffing needs to accommodate quicker appointments.

Indexed as

Attitude of Health PersonnelHIV InfectionsQualitative ResearchAdultAnti-HIV AgentsFemaleHealth PersonnelHumansMaleMiddle AgedNorth CarolinaTime-to-TreatmentAnti-HIV AgentsART therapyhealthcare providersHIVpeople living with HIV (PLWH)rapid treatment initiation

Identifiers

PMID39234631
PMCPMC11378170

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.