Evidence map›Paper›PMID 39234246›Full record

Trial reportFrontiers in immunology2024

Evaluation of efficacy and safety of

Yue Niu, Jing Li, Hongwei Qian, Chunli Liang, Xinyi Shi, Shurui Bu

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07505329 (An Intervention Study in Healthy Infants Aged 0-6 Months With Probiotics Lacticaseibacillus Rhamnosus LRa05), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07505329 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

An Intervention Study in Healthy Infants Aged 0-6 Months With Probiotics Lacticaseibacillus Rhamnosus LRa05 (LRa05) and Bifidobacterium Animalis Subsp. Lactis BLa80 (BLa80) vs. Placebo, for Promoting Gut Microbiome Development.

TypeinterventionalSponsorUniversity College CorkRan2026 to 2028Enrolled300ConditionsLess Than 3 Months Old, Healthy InfantsArmsPlacebo (maltodextrin), Probiotic
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Beyond Antibiotics: Alternative Strategies TargetingExpert reviews in molecular medicine · 2026
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yue Niu *Department of Gastroenterology, Jinshan Hospital, Fudan University, Shanghai, China.
Jing Li *Department of Gastroenterology, Jinshan Hospital, Fudan University, Shanghai, China.
Hongwei QianDepartment of General Practice, Shihua Community Health Service Center in Jinshan District, Shanghai, China.
Chunli LiangDepartment of Gastroenterology, Jinshan Hospital, Fudan University, Shanghai, China.
Xinyi ShiDepartment of General Practice, Shihua Community Health Service Center in Jinshan District, Shanghai, China.
Shurui BuDepartment of Gastroenterology, Jinshan Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: This study aims to evaluate the efficacy of Methods: Results: The LRa05 group exhibited a trend toward higher Conclusion: Although LRa05 did not significantly improve the success rate of Clinical Trial Registration: http://www.chictr.org.cn, identifier ChiCTR2300072220.

Indexed as

Helicobacter InfectionsHelicobacter pyloriLacticaseibacillus rhamnosusProbioticsAdultAnti-Bacterial AgentsDouble-Blind MethodDrug Therapy, CombinationFemaleGastrointestinal MicrobiomeHumansMaleMiddle AgedTreatment OutcomeAnti-Bacterial Agentsbismuth quadruple therapyeradicationgut microbiotaHelicobacter pyloriLacticaseibacillus rhamnosus LRa05

Identifiers

PMID39234246
PMCPMC11371625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.