ArticleFrontiers in medicine2024
Association between the inflammatory burden index and rheumatoid arthritis and its all-cause mortality: data from NHANES 1999-2018.
Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Inflammatory burden index predicts arteriogenic erectile dysfunction: a mediation analysis involving the TyG index.Sexual medicine · 2026Article
- Inflammation burden index as a complementary marker for the assessment of hepatic steatosis and fibrosis: evidence from NHANES 2017-2018.Abdominal radiology (New York) · 2026Article
- Innovative Inflammatory Burden Index for identification of high mortality risk in patients with pulmonary embolism: a large retrospective cohort study.BMJ open respiratory research · 2026Article
- Differences in Cause-Specific Mortality in Patients With Rheumatoid Arthritis by Sex and Seropositivity.The Journal of rheumatology · 2025Article
- Associations of inflammatory burden index with the prevalence and mortality of asthma in adults: a population based study.Journal of thoracic disease · 2025Article
- Association between the inflammatory burden index and erectile dysfunction: a cross-sectional study based on NHANES 2001-2004.Journal of health, population, and nutrition · 2025Article
- Association between rheumatoid arthritis and kidney stones: A cross-sectional study of NHANES 2007-2020.Arthritis research & therapy · 2025Article
- Association between inflammation indicators and albuminuria in US adults: a cross-sectional study.Scientific reports · 2025Article
- Association of the inflammatory burden index with the risk of pre-diabetes and diabetes mellitus: a cross-sectional study.BMC endocrine disorders · 2025Article
- Inflammatory burden index (IBI) and body roundness index (BRI) in gallstone risk prediction: insights from NHANES 2017-2020.Lipids in health and disease · 2025Article
- The impact of inflammatory burden index on the prognosis in acute decompensated heart failure: evidence from a cohort study in Jiangxi, China.Frontiers in cardiovascular medicine · 2025Article
- The role of C-reactive protein in predicting all-cause mortality among Chinese arthritis patients: implications for public health education and promotion.Frontiers in public health · 2025Article
- Inflammatory Burden Index Associated with Recurrence of Atrial Fibrillation After Radiofrequency Catheter Ablation.Therapeutics and clinical risk management · 2025Article
- Association and Predictive Ability between Inflammatory Burden Index and Fever Following Endobronchial Forceps Biopsy in Lung Cancer Patients.Journal of inflammation research · 2025Article
- Association between the composite dietary antioxidant index and all-cause mortality in individuals with osteoarthritis via NHANES data.Scientific reports · 2024Article
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8 authors.
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Abstract
Background and aims: Rheumatoid arthritis (RA) is a prevalent chronic autoimmune disease characterized by chronic inflammation. The Inflammatory Burden Index (IBI) is a newly proposed comprehensive inflammation index used to assess systemic inflammation. The relationship between IBI and RA, as well as its all-cause mortality, remains unclear. The objective of this study was to examine the correlation between IBI and RA and to analyze the association between IBI and all-cause mortality in RA. Methods: The study comprehensively analyzes adult data from the National Health and Nutrition Examination Survey (NHANES) spanning 1999 to 2018. The participants' IBI was calculated using the formula IBI = CRP * neutrophils/lymphocytes. Three models were constructed to investigate the relationship between IBI and the prevalence of RA. Nonlinear relationships were determined using restricted cubic spline curves. Stratified analyses and interaction tests were used to explore the relationship between RA and IBI in different subgroups. The same data analyses were applied to investigate the association between IBI and RA all-cause mortality. Results: The data analyses revealed a stable positive and nonlinear correlation between IBI and the risk of RA, as well as a positive, nonlinear, J-shaped association between IBI and RA all-cause mortality. The correlation and association were consistent across most subgroups, and multiple covariates had no effect on the results. No significant effect of multiple covariates on the association was found through interaction tests. Conclusion: Our study has demonstrated a positive correlation between the prevalence of RA and all-cause mortality with the IBI index. This suggests that lower levels of inflammation in the body are associated with a reduced risk of RA prevalence and all-cause mortality. Further prospective studies are required to explore the mechanisms involved.
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