Evidence map›Paper›PMID 39233861›Full record

ReviewWorld journal of otorhinolaryngology - head and neck surgery2024

Eosinophil extracellular traps in respiratory ailment: Pathogenic mechanisms and clinical translation.

Shun-Yu Wu, Bo-Yu Cai, Tian-Yu Wang, Zhi-Wen Cao, Hu Peng, Huan-Hai Liu

Abstract readReview
In one paragraph

Review in World journal of otorhinolaryngology - head and neck surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Eosinophils in Rheumatoid Arthritis: A Multifaceted Role in the Pathogenesis of the Disease.Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al · 2025
    Article
  4. Article
  5. Eosinophil extracellular traps in respiratory ailment: Pathogenic mechanisms and clinical translation.World journal of otorhinolaryngology - head and neck surgery · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shun-Yu WuDepartment of Otolaryngology The Second Affiliated Hospital of the Naval Military Medical University (Shanghai Changzheng Hospital) Shanghai China.ORCID 0000-0003-2793-7015
Bo-Yu CaiDepartment of Otolaryngology The Second Affiliated Hospital of the Naval Military Medical University (Shanghai Changzheng Hospital) Shanghai China.
Tian-Yu WangDepartment of Otolaryngology The Second Affiliated Hospital of the Naval Military Medical University (Shanghai Changzheng Hospital) Shanghai China.
Zhi-Wen CaoDepartment of Otolaryngology The Second Affiliated Hospital of the Naval Military Medical University (Shanghai Changzheng Hospital) Shanghai China.
Hu PengDepartment of Otolaryngology The Second Affiliated Hospital of the Naval Military Medical University (Shanghai Changzheng Hospital) Shanghai China.
Huan-Hai LiuDepartment of Otolaryngology The Second Affiliated Hospital of the Naval Military Medical University (Shanghai Changzheng Hospital) Shanghai China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Eosinophilic extracellular traps (EETs) are reticular complexes comprising deoxyribonucleic-Acid (DNA) fibers and granule proteins. Aims: EETs play a crucial role in antimicrobial host responses and are pathogenic when overproduced or under degraded. EETs created by eosinophils appear to enable vital immune responses against extra-cellular pathogens, nevertheless, trap overproduction is evident in pathology. Materials & Methods: As considerably research is performed, new data affirmed that EETs can alter the outcome of respiratory ailment. Results: We probe into the disclosure and specificity of EETs produced in reaction to various stimuli and propose a role for those frameworks in ailment pathogenesis and the establishment of chronic, unresolved inflammation. Discussion: Whether EETs can be used as a prospective brand-new target for the diagnosis, treatment and prognosis of respiratory ailments is a scientific theme worth studying. Conclusion: We probe into the disclosure and specificity of EETs produced in reaction to various stimuli and propose a role for those frameworks in ailment pathogenesis and the establishment of chronic, unresolved inflammation.

Indexed as

cytolysisdegranulationeosinophil extracellular trapseosinophilsrespiratory ailments

Identifiers

PMID39233861
PMCPMC11369806

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.