Evidence map›Paper›PMID 39233610›Full record

ArticleAnnals of medicine2024

Evaluation of optical coherence tomography angiography and pattern and flash electroretinography in diabetes mellitus without retinopathy.

Burcu Polat Gültekin, Mualla Hamurcu

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Article in Annals of medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Association and Multimodal Model of Retinal Mid-Peripheral Capillary Free Zones with Structural and Functional Parameters in Diabetic Patients Without Clinical Retinopathy.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Burcu Polat GültekinDepartment of Ophthalmology, Ankara Sehir Hastanesi, Cankaya, Turkey.ORCID 0000-0001-9121-3041
Mualla HamurcuAnkara Bilkent City Hospital Ophthalmology Clinic, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the findings and the correlation of optical coherence tomography angiography and pattern and flash electroretinography in diabetes mellitus without retinopathy.

methodsSeventy-six eyes of 38 diabetic patients and age- and gender-matched control subjects were included in the study. The foveal avascular zone (FAZ), whole, foveal, parafoveal and perifoveal vascular densities of the superficial capillary plexus (SCP), deep capillary plexus (DCP) and choriocapillary plexus (CCP) layers were analyzed using optical coherence tomography angiography (OCTA). The amplitudes and implicit times of P50 and N95 waves of the pattern ERG (pERG) and the amplitudes and implicit times of the scotopic and photopic b-waves and oscillatory potentials (OP) of the flash ERG (fERG) tests were evaluated using the Metrovision brand monpack model device.

resultsThe mean age of the patients was 59.7 ± 7.9 [range 43-79] years. Eighteen (47%) of the patients were female and 20 (53%) were male. The mean duration of diabetes was 7.45 ± 6.2 [range 1-20] years. No significant difference in FAZ area was found between study subjects and controls. Vascular density (VD) values of the superficial capillary plexus (SCP) layer were significantly lower (whole VD, 44.7 ± 3.3 vs. 46.6 ± 3.2%,

conclusionOCTA revealed decreased superficial vascular densities with the onset of the metabolic process of diabetes mellitus. As a result of these structural changes, lower scotopic and photopic amplitudes, decreased OP amplitudes, and prolonged implicit times in flash ERG were obtained.

Indexed as

ElectroretinographyTomography, Optical CoherenceAdultAgedCase-Control StudiesDiabetes MellitusDiabetic RetinopathyFemaleFluorescein AngiographyFovea CentralisHumansMaleMiddle AgedRetinaRetinal VesselsDiabetes mellitusflash electroretinographyoptical coherence tomography angiographypattern electroretinographyretinopathy

Identifiers

PMID39233610
PMCPMC11378657

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