Evidence map›Paper›PMID 39233453›Full record

ReviewClinical transplantation and research2024

Animal models for transplant immunology: bridging bench to bedside.

Minseok Kang, Hwon Kyum Park, Kyeong Sik Kim, Dongho Choi

Abstract readReview
In one paragraph

Review in Clinical transplantation and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trajectory-based weight modeling distinguishes pathologic weight loss and predicts adverse events in nonhuman primate allogeneic kidney transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
    Article
  2. Article
  3. A standardised and reproducible method forAnnals of translational medicine · 2026
    Article
  4. Review
  5. Thermal Rejection Assessment: New Strategies for Early Detection.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Minseok KangDepartment of Surgery, Hanyang University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0003-3736-625X
Hwon Kyum ParkDepartment of Surgery, Hanyang University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0004-3320-682X
Kyeong Sik KimDepartment of Surgery, Hanyang University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-1463-8617
Dongho ChoiDepartment of Surgery, Hanyang University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-1255-1964

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The progress of transplantation has been propelled forward by animal experiments. Animal models have not only provided opportunities to understand complex immune mechanisms in transplantation but also served as a platform to assess therapeutic interventions. While small animals have been instrumental in uncovering new therapeutic concepts related to immunosuppression and immune tolerance, the progression to human trials has largely been driven by studies in large animals. Recent research has begun to explore the potential of porcine organs to address the shortage of available organs. The consistent progress in transplant immunology research can be attributed to a thorough understanding of animal models. This review provides a comprehensive overview of the available animal models, detailing their modifications, strengths, and weaknesses, as well as their historical applications, to aid researchers in selecting the most suitable model for their specific research needs.

Indexed as

Animal modelsGraft rejectionImmune toleranceImmunosuppression therapyXenotransplantation

Identifiers

PMID39233453
PMCPMC11732767

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.