Evidence map›Paper›PMID 39233375›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2024

Alpha oscillations during visual selective attention are aberrant in youth and adults with cerebral palsy.

Rashelle M Hoffman, Michael P Trevarrow, Brandon J Lew, Tony W Wilson, Max J Kurz

Abstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Rashelle M HoffmanMunroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, 6902 Pine St, Omaha, NE 68106, United States.
Michael P TrevarrowInstitute for Human Neuroscience, Boys Town National Research Hospital, 14090 Mother Teresa Lane, Omaha, NE 68010, United States.
Brandon J LewInstitute for Human Neuroscience, Boys Town National Research Hospital, 14090 Mother Teresa Lane, Omaha, NE 68010, United States.
Tony W WilsonInstitute for Human Neuroscience, Boys Town National Research Hospital, 14090 Mother Teresa Lane, Omaha, NE 68010, United States.
Max J KurzInstitute for Human Neuroscience, Boys Town National Research Hospital, 14090 Mother Teresa Lane, Omaha, NE 68010, United States.ORCID 0000-0001-7040-5474

Funding

Stress-Induced Aberrations in the Mitochondrial Redox Environment Impact Developing Neural Circuits Supporting Cognitive ControlP20GM144641 · NIGMS · FATHER FLANAGAN'S BOYS' HOME · PI Giorgia Picci · 2022 to 2026
$15.1M
NEUROPHYSIOLOGY OF RESPONDERS AND NON-RESPONDERS WITH CEREBRAL PALSYR01HD101833 · NICHD · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KURZ, MAX J · 2020 to 2024
$3.2M
Dynamic Imaging of Cerebral Palsy GaitR01HD108205 · NICHD · FATHER FLANAGAN'S BOYS' HOME · PI Max J Kurz · 2022 to 2026
$3.2M
Foundation for Physical TherapyNICHD NIH HHS R01 HD101833NICHD NIH HHS R01 HD108205NIGMS NIH HHS P20 GM144641NIH HHS R01HD108205Promotion of Doctoral Studies
6 · The paper itself

Abstract

Our understanding of the neurobiology underlying cognitive dysfunction in persons with cerebral palsy is very limited, especially in the neurocognitive domain of visual selective attention. This investigation utilized magnetoencephalography and an Eriksen arrow-based flanker task to quantify the dynamics underlying selective attention in a cohort of youth and adults with cerebral palsy (n = 31; age range = 9 to 47 yr) and neurotypical controls (n = 38; age range = 11 to 49 yr). The magnetoencephalography data were transformed into the time-frequency domain to identify neural oscillatory responses and imaged using a beamforming approach. The behavioral results indicated that all participants exhibited a flanker effect (greater response time for the incongruent compared to congruent condition) and that individuals with cerebral palsy were slower and less accurate during task performance. We computed interference maps to focus on the attentional component and found aberrant alpha (8 to 14 Hz) oscillations in the right primary visual cortices in the group with cerebral palsy. Alpha and theta (4 to 7 Hz) oscillations were also seen in the left and right insula, and these oscillations varied with age across all participants. Overall, persons with cerebral palsy exhibit deficiencies in the cortical dynamics serving visual selective attention, but these aberrations do not appear to be uniquely affected by age.

Indexed as

Alpha RhythmAttentionCerebral PalsyMagnetoencephalographyAdolescentAdultChildFemaleHumansMaleMiddle AgedPhotic StimulationReaction TimeVisual PerceptionYoung AdultcognitionflankermagnetoencephalographyMEGneuroimaging

Identifiers

PMID39233375
PMCPMC11374708

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.