ArticleBMC medicine2024
Cancer incidence (2000-2020) among individuals under 35: an emerging sex disparity in oncology.
Article in BMC medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Sex differences in non-reproductive cancers: mechanistic roles of sex-hormone signaling.Cell communication and signaling : CCS · 2026Review
- Pronounced ethnic and sex disparities in gastric cancer burden and healthcare utilization in Inner Mongolia: a 9-year population-based cohort study.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026Article
- <p>Unveiling sex differences in pancreatic ductal adenocarcinoma: Current evidence and future directions (Review)</p>.International journal of oncology · 2026Review
- Definition of Sporadic Early-Onset Invasive Solid Organ Cancers in Adults.Oncology and therapy · 2026Article
- Estimating and Ranking of Common Cancers in South Africa's Eastern Cape and Mpumalanga Provinces: A Patient Survey in Three Referral Hospitals.International journal of environmental research and public health · 2026Article
- Shifting epidemiology of pancreatic cancer in Southeast Spain (1983-2018): emerging patterns in younger women and neuroendocrine neoplasms.Frontiers in oncology · 2026Article
- An Unusual Case of Pancreatic Ductal Adenocarcinoma With Synchronous Rectal Metastasis in a Younger Female.Case reports in gastrointestinal medicine · 2026Article
- Pancreatic Neuroendocrine and Exocrine Cancer Incidence, and Stage at Diagnosis Before, During, and After the COVID-19 Pandemic, United States, 2019-2022.Journal of registry management · 2026Article
- What cancers are increasing in young adults: a population-based study of incidence trends in adults 20-49 years old in the South of Spain.BMC public health · 2025Article
- Assessment of the reliability and quality of pancreatic cancer related short videos on mainstream platforms: cross-sectional study.BMC cancer · 2025Article
- Analysis of screen-detected pulmonary nodules before and after the novel coronavirus epidemic: a multicenter retrospective cohort study.Frontiers in oncology · 2025Article
- Comment on 'AWGC2023 Cachexia Consensus as a Valuable Tool for Predicting Prognosis and Burden in Chinese Patients With Cancer' by Xie et al.Journal of cachexia, sarcopenia and muscle · 2024Article
- Sex-Related Differences in Pancreatic Ductal Adenocarcinoma Progression and Response to Therapy.International journal of molecular sciences · 2024Review
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAggressive malignancies, such as pancreatic cancer, are increasingly impacting young, female populations. Our investigation centered on whether the observed trends in cancer incidence were unique to pancreatic cancer or indicative of a broader trend across various cancer types. To delve deeper into this phenomenon, we analyzed cancer incidence trends across different age and sex groups. Furthermore, we explored differences in cancer incidence within specific young subgroups aged 18 to 26 and 27 to 34, to better understand the emerging incidence trend among young individuals.
methodsThis study collected cancer incidence data from one of the Surveillance, Epidemiology, and End Results cancer registry databases (SEER22), with 10,183,928 total cases from 2000 to 2020. Data were analyzed through Joinpoint trend analysis approach to evaluate sex- and age-specific trends in cancer incidence. Exposure rates were reported as Average Annual Percentage Changes (AAPCs).
resultsThe analysis revealed significant age and sex-specific disparities, particularly among individuals aged 18-26 and 27-34. Pancreatic cancer incidence rates increased more in females aged 18-26 (AAPC, 9.37% [95% CI, 7.36-11.41%]; p < .0001) than in males (4.43% [95% CI, 2.36-6.53%]; p < .0001). Notably, among gender, age, and other malignancies, young females had the highest AAPCs for pancreatic cancer. Additionally, the incidence of gastric cancer, myeloma, and colorectal malignancies also showed higher AAPCs in young females compared to males.
conclusionsRecognizing emerging risk populations for highly lethal malignancies is crucial for early detection and effective disease management.
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