Evidence map›Paper›PMID 39232703›Full record

Trial reportBMC oral health2024

Analgesic effect of ultrasound-guided extraoral mandibular nerve block compared to intraoral conductive block of the inferior alveolar nerve after lower third molar alveolectomy: a clinical prospective study.

Marija Martinus, Slobodan Mihaljevic, Kresimir Reiner, Zeljko Verzak, Monika Kocman Panic, Aleksandra Strahija, Vicko Gluncic, Ivan Kresimir Lukic, Anita Lukic

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06009302 (Analgesic Effects of Extraoral Ultrasound Block of Mandibular Nerve for the Extraction of Lower Third Molars), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06009302 nacompletednot on this map

Analgesic Effects of Extraoral Ultrasound Block of Mandibular Nerve for the Extraction of Lower Third Molars

TypeinterventionalSponsorVarazdin General HospitalRan2023 to 2023Enrolled36ConditionsMolar, Impacted TeethArmsUS guided block of mandibular nerve, Intraoral block of lower alveolar nerve
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marija MartinusDepartment of Anesthesiology, Reanimatology, and Intensive Medicine, Varazdin General Hospital, 1 I. Mestrovica Street, Varazdin, 42000, Croatia.
Slobodan MihaljevicClinic of Anesthesiology, Reanimatology, Intensive Care and Pain Therapy, University Clinical Hospital Centre Zagreb, Zagreb, Croatia.
Kresimir ReinerClinic of Anesthesiology, Reanimatology, Intensive Care and Pain Therapy, University Clinical Hospital Centre Zagreb, Zagreb, Croatia.
Zeljko VerzakUniversity of Zagreb School of Dental Medicine, Zagreb, Croatia.
Monika Kocman PanicDepartment of Anesthesiology, Reanimatology, and Intensive Medicine, Varazdin General Hospital, 1 I. Mestrovica Street, Varazdin, 42000, Croatia.
Aleksandra StrahijaDepartment Otorhinolaryngology, Varazdin General Hospital, Varazdin, Croatia.
Vicko GluncicDepartment of Anesthesia, Advocate Illinois Masonic Medical Center, Ilinois, USA.
Ivan Kresimir LukicCatholic University of Croatia, Zagreb, Croatia.
Anita LukicDepartment of Anesthesiology, Reanimatology, and Intensive Medicine, Varazdin General Hospital, 1 I. Mestrovica Street, Varazdin, 42000, Croatia. lukic.anita@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe analgesia after lower third molar alveolectomy is based on the use of non-steroidal anti-inflammatory drugs (NSAIDs) that have significant risks, and are contraindicated in the third trimester of pregnancy. Aiming to reduce NSAIDs use after this surgery, we quantified analgesic effects of ultrasound (US)-guided extraoral mandibular nerve block.

methodsThirty-six patients were equally allocated to the experimental or control group, based on their willingness to receive experimental US-guided extraoral mandibular nerve block for postoperative analgesia. The experimental block applied prior to lower third molar alveolectomy, was followed by standard intraoral inferior alveolar nerve block. In the control group, patients received only intraoral block of inferior alveolar nerve. All patients reported pain level (visual analogue scale, VAS) right after the application of blocks. The next day, patients reported duration of pain-free time and the use of analgesic.

resultsThe US-guided extraoral mandibular nerve block prolonged the pain-free time to 8 h (vs. 4 in control group, P < 0.001) and reduced NSAIDs use (12 patients needed analgesic in experimental vs. 17 patients in control group, P = 0.038). The application of experimental block was less painful (VAS = 2) than the application of intraoral inferior alveolar nerve block (VAS = 4, P = 0.011). In 8/18 patients in the experimental group US-guided extraoral mandibular nerve block solely achieved adequate surgical anesthesia.

conclusionUS-guided extraoral mandibular nerve block prolonged pain-free period and reduced the use of NSAIDs after lower third molar alveolectomy, thus proving to be successful analgesia method for this dental surgery. CLINICAL

trial registrationhttps://classic. CLINICALTRIALS: gov/ct2/show/NCT06009302 , identification number: NCT06009302, date of registration: 18/08/2023.

Indexed as

Mandibular NerveMolar, ThirdNerve BlockPostoperative PainAdultAnti-Inflammatory Agents, Non-SteroidalFemaleHumansMalePain MeasurementProspective StudiesTooth ExtractionUltrasonography, InterventionalYoung AdultAnti-Inflammatory Agents, Non-SteroidalDental anesthesiaImpactedInferior alveolar nerveMandibular nerveRegional anesthesiaToothUltrasound

Identifiers

PMID39232703
PMCPMC11375996

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.