ArticleBMC nephrology2024
Case report: membranoproliferative glomerulonephritis associated with Q fever causing chronic endocarditis.
Article in BMC nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Retrospective Analysis of Chronic Q Fever Cases at a Tertiary Care Center From 2007 to 2023.Open forum infectious diseases · 2026Article
- Q fever endocarditis complicating biventricular failure: diagnostic and therapeutic insights from a case report and literature review.Frontiers in medicine · 2026Article
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Authors and funding
4 authors.
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Abstract
backgroundMembranoproliferative glomerulonephritis is a rare entity which can be a result from autoimmune diseases, caused by various medications and infections. CASE PRESENTATION: We herein present the case of a 62-year-old male patient who presented with fatigue and was found to have severe anemia, impaired renal function, and nephrotic syndrome. A renal biopsy revealed membranoproliferative glomerulonephritis (MPGN) of the immune complex type with activation of the classical complement pathway. Further investigations led to the diagnosis of a chronic Coxiella burnetii-infection (Q fever), likely acquired during cycling trips in a region known for intensive sheep farming. Additionally, the patient was found to have a post endocarditic destructive bicuspid aortic valve caused by this pathogen. Treatment with hydroxychloroquine and doxycycline was administered for a duration of 24 months. The aortic valve was replaced successfully and the patient recovered completely.
conclusionsEarly detection and targeted treatment of this life-threatening disease is crucial for complete recovery of the patient.
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