Evidence map›Paper›PMID 39232193›Full record

ArticleScientific reports2024

Natural modulation of redox status throughout the ontogeny of Amazon frog Physalaemus ephippifer (Anura, Leptodactylidae).

João Pedro Pantoja Monteiro, Carla Carolina Miranda Dos Santos, João Paulo Moura de Queiroz, Rafael Anaisce das Chagas, Sarita Nunes Loureiro, Alana Rodrigues Nauar, Maria Luiza Cunha Souza-Ferreira, Adauto Lima Cardoso, Cesar Martins, Tamara G Petrović and 3 more

Abstract read
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In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

João Pedro Pantoja MonteiroLaboratório de Pesquisas em Monitoramento Ambiental Marinho e Laboratório de Ecotoxicologia, Instituto de Ciências Biológicas, Universidade Federal do Pará (UFPA), Rua Augusto Corrêa 01, Belém, PA, 66075-110, Brazil.
Carla Carolina Miranda Dos SantosLaboratório de Pesquisas em Monitoramento Ambiental Marinho e Laboratório de Ecotoxicologia, Instituto de Ciências Biológicas, Universidade Federal do Pará (UFPA), Rua Augusto Corrêa 01, Belém, PA, 66075-110, Brazil.
João Paulo Moura de QueirozLaboratório de Pesquisas em Monitoramento Ambiental Marinho e Laboratório de Ecotoxicologia, Instituto de Ciências Biológicas, Universidade Federal do Pará (UFPA), Rua Augusto Corrêa 01, Belém, PA, 66075-110, Brazil.
Rafael Anaisce das ChagasLaboratório de Pesquisas em Monitoramento Ambiental Marinho e Laboratório de Ecotoxicologia, Instituto de Ciências Biológicas, Universidade Federal do Pará (UFPA), Rua Augusto Corrêa 01, Belém, PA, 66075-110, Brazil.
Sarita Nunes LoureiroLaboratório de Pesquisas em Monitoramento Ambiental Marinho e Laboratório de Ecotoxicologia, Instituto de Ciências Biológicas, Universidade Federal do Pará (UFPA), Rua Augusto Corrêa 01, Belém, PA, 66075-110, Brazil.
Alana Rodrigues NauarLaboratório de Pesquisas em Monitoramento Ambiental Marinho e Laboratório de Ecotoxicologia, Instituto de Ciências Biológicas, Universidade Federal do Pará (UFPA), Rua Augusto Corrêa 01, Belém, PA, 66075-110, Brazil.
Maria Luiza Cunha Souza-FerreiraLaboratório de Pesquisas em Monitoramento Ambiental Marinho e Laboratório de Ecotoxicologia, Instituto de Ciências Biológicas, Universidade Federal do Pará (UFPA), Rua Augusto Corrêa 01, Belém, PA, 66075-110, Brazil.
Adauto Lima CardosoDepartamento de Biologia Estrutural e Funcional, Instituto de Biociências de Botucatu, Universidade Estadual Paulista, São Paulo, Brazil.
Cesar MartinsDepartamento de Biologia Estrutural e Funcional, Instituto de Biociências de Botucatu, Universidade Estadual Paulista, São Paulo, Brazil.
Tamara G PetrovićDepartment of Physiology, Institute for Biological Research "Siniša Stanković" - National Institute of the Republic of Serbia, University of Belgrade, Bulevar Despota Stefana 142, 11108, Belgrade, Serbia.
Marko D ProkićDepartment of Physiology, Institute for Biological Research "Siniša Stanković" - National Institute of the Republic of Serbia, University of Belgrade, Bulevar Despota Stefana 142, 11108, Belgrade, Serbia.
Verônica Regina Lobato Oliveira-BahiaLaboratório Multidisciplinar de Morfofisiologia Animal, Instituto de Ciências Biológicas (UFPA), Belém, Brazil.
Lílian Lund AmadoLaboratório de Pesquisas em Monitoramento Ambiental Marinho e Laboratório de Ecotoxicologia, Instituto de Ciências Biológicas, Universidade Federal do Pará (UFPA), Rua Augusto Corrêa 01, Belém, PA, 66075-110, Brazil. lilian.amado@gmail.com.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 309628/2022-9
6 · The paper itself

Abstract

During their development, amphibians undergo various physiological processes that may affect their susceptibility to environmental pollutants. Naturally occurring fluctuations caused by developmental events are often overlooked in ecotoxicological studies. Our aim is to investigate how biomarkers of oxidative stress are modulated at different stages of larval development in the Amazonian amphibian species, Physalaemus ephippifer. The premetamorphosis, prometamorphosis and metamorphic climax stages were used to analyze total antioxidant capacity (ACAP), glutathione S-transferase (GST) activity, lipid peroxidation (LPO) levels and the expression of genes nrf2, gst, gsr (glutathione reductase) and gclc (glycine-cysteine ligase, catalytic subunit). Although there was no difference in ACAP and the genes expression among the studied stages, individuals from the premetamorphosis and prometamorphosis showed higher GST activity than ones under the climax. LPO levels were highest in individuals from the metamorphic climax. The present study suggests that the oxidative status changes during ontogeny of P. ephippifer tadpoles, especially during the metamorphic climax, the most demanding developmental phase. Variations in the redox balance at different developmental stages may lead to a divergent response to pollution. Therefore, we recommend that studies using anuran larvae as biomonitors consider possible physiological differences during ontogeny in their respective analyses.

Indexed as

AnuraGlutathione TransferaseLarvaLipid PeroxidationOxidation-ReductionOxidative StressAnimalsAntioxidantsBiomarkersMetamorphosis, BiologicalAntioxidantsBiomarkersGlutathione TransferaseAmazonAnuransEcotoxicologyOxidative stressPhysiologyTadpoles

Identifiers

PMID39232193
PMCPMC11375210

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.