Evidence map›Paper›PMID 39232178›Full record

ArticleScientific reports2024

Multi-modality multi-task model for mRS prediction using diffusion-weighted resonance imaging.

In-Seo Park, Seongheon Kim, Jae-Won Jang, Sang-Won Park, Na-Young Yeo, Soo Young Seo, Inyeop Jeon, Seung-Ho Shin, Yoon Kim, Hyun-Soo Choi and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

In-Seo Park *Department of Convergence Security, Kangwon National University, Chuncheon, 24253, Korea.
Seongheon Kim *Department of Medical Informatics, Kangwon National University, Chuncheon, 24253, Korea.
Jae-Won JangDepartment of Convergence Security, Kangwon National University, Chuncheon, 24253, Korea.
Sang-Won ParkDepartment of Medical Informatics, Kangwon National University, Chuncheon, 24253, Korea.
Na-Young YeoDepartment of Medical Bigdata Convergence, Kangwon National University, Chuncheon, 24253, Korea.
Soo Young SeoInstitute of New Frontier Research Team, Hallym University College of Medicine, Chuncheon, 24252, Korea.
Inyeop JeonChuncheon Artificial Intelligence Center, Chuncheon Sacred Heart Hospital, Chuncheon, 24253, Korea.
Seung-Ho ShinChuncheon Artificial Intelligence Center, Chuncheon Sacred Heart Hospital, Chuncheon, 24253, Korea.
Yoon KimDepartment of Computer Science and Engineering, Kangwon National University, Chuncheon, 24253, Korea.
Hyun-Soo ChoiDepartment of Computer Science and Engineering, Seoul National University of Science and Technology, Seoul, South Korea. choi.hyunsoo@seoultech.ac.kr.
Chulho KimDepartment of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, 24253, Korea. gumdol52@hallym.or.kr.

Funding

Korea government (Ministry of Science and ICT) 2022R1A5A708390811Korea government (Ministry of Science and ICT) 2022R1F1A1076454Ministry of Education (MOE) 2023RIS-005Ministry of Health & Welfare, Republic of Korea HR21C0198
6 · The paper itself

Abstract

This study focuses on predicting the prognosis of acute ischemic stroke patients with focal neurologic symptoms using a combination of diffusion-weighted magnetic resonance imaging (DWI) and clinical information. The primary outcome is a poor functional outcome defined by a modified Rankin Scale (mRS) score of 3-6 after 3 months of stroke. Employing nnUnet for DWI lesion segmentation, the study utilizes both multi-task and multi-modality methodologies, integrating DWI and clinical data for prognosis prediction. Integrating the two modalities was shown to improve performance by 0.04 compared to using DWI only. The model achieves notable performance metrics, with a dice score of 0.7375 for lesion segmentation and an area under the curve of 0.8080 for mRS prediction. These results surpass existing scoring systems, showing a 0.16 improvement over the Totaled Health Risks in Vascular Events score. The study further employs grad-class activation maps to identify critical brain regions influencing mRS scores. Analysis of the feature map reveals the efficacy of the multi-tasking nnUnet in predicting poor outcomes, providing insights into the interplay between DWI and clinical data. In conclusion, the integrated approach demonstrates significant advancements in prognosis prediction for cerebral infarction patients, offering a superior alternative to current scoring systems.

Indexed as

Diffusion Magnetic Resonance ImagingAgedBrainFemaleHumansIschemic StrokeMaleMiddle AgedPrognosisStroke

Identifiers

PMID39232178
PMCPMC11374799

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.