Evidence map›Paper›PMID 39232174›Full record

ArticleNature2024

Recurrent evolution and selection shape structural diversity at the amylase locus.

Davide Bolognini, Alma Halgren, Runyang Nicolas Lou, Alessandro Raveane, Joana L Rocha, Andrea Guarracino, Nicole Soranzo, Chen-Shan Chin, Erik Garrison, Peter H Sudmant

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. Ancient DNA and Human Physiology.Physiology (Bethesda, Md.) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. High-coverage ancient genomes reveal divergent population histories and prehistoric starch-related genetic variation in Japan.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Article
  10. The genetic foundations of convergent traits.Nature reviews. Genetics · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Davide Bolognini *Human Technopole, Milan, Italy.ORCID 0000-0002-8735-8093
Alma Halgren *Department of Integrative Biology, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0002-7112-5930
Runyang Nicolas Lou *Department of Integrative Biology, University of California Berkeley, Berkeley, CA, USA.
Alessandro Raveane *Human Technopole, Milan, Italy.ORCID 0000-0002-8322-5461
Joana L Rocha *Department of Integrative Biology, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0003-3266-6328
Andrea GuarracinoDepartment of Genetics, Genomics, and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA.ORCID 0000-0001-9744-131X
Nicole SoranzoHuman Technopole, Milan, Italy.
Chen-Shan ChinFoundation for Biological Data Science, Belmont, CA, USA.ORCID 0000-0003-4394-2455
Erik GarrisonDepartment of Genetics, Genomics, and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA. egarris5@uthsc.edu.ORCID 0000-0003-3821-631X
Peter H SudmantDepartment of Integrative Biology, University of California Berkeley, Berkeley, CA, USA. psudmant@berkeley.edu.ORCID 0000-0002-9573-8248

Funding

A Unified High Performance Web Service for Systems Genetics and Precision MedicineR01GM123489 · NIGMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI PRINS, PJOTR, SEN, SAUNAK · 2017 to 2024
$3.7M
System genetics of menthol and nicotine addictionU01DA047638 · NIDA · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI CHEN, HAO, WILLIAMS, ROBERT W. · 2019 to 2023
$3.1M
Pangenomics of nicotine abuse in the hybrid rat diversity panelU01DA057530 · NIDA · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI Hao Chen, BURT M SHARP · 2023 to 2026
$2.8M
The evolution and diversity of mutation, molecular fidelity, and genome structureR35GM142916 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Peter Heshedahl Sudmant · 2021 to 2026
$2.5M
A compendium of complete primate reference genomes to facilitate conservation, genomics, and ecologyR01HG013017 · NHGRI · UNIVERSITY OF CALIFORNIA BERKELEY · PI Erik Garrison, Matthew William Mitchell · 2023 to 2026
$1.9M
Building Tools and Community to Make Pangenomes AccessibleU01HG013760 · NHGRI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI GARRISON, ERIK · 2024 to 2024
$1.6M
NHGRI NIH HHS R01 HG013017NHGRI NIH HHS U01 HG013760NIDA NIH HHS U01 DA047638NIDA NIH HHS U01 DA057530NIGMS NIH HHS R01 GM123489NIGMS NIH HHS R35 GM142916
6 · The paper itself

Abstract

The adoption of agriculture triggered a rapid shift towards starch-rich diets in human populations

Indexed as

AgricultureAmylasesEvolution, MolecularGene DosageGenome, HumanHaplotypesSelection, GeneticDNA, AncientGene DeletionGene DuplicationGenetic LociHistory, AncientHumansHuntingMutation RatePancreatic alpha-AmylasesAMY2A protein, humanAmylasesDNA, AncientPancreatic alpha-Amylases

Identifiers

PMID39232174
PMCPMC11485256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.