ArticleNature2024
An aberrant immune-epithelial progenitor niche drives viral lung sequelae.
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Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
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60citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
60 citing papers in PubMed.
- Monocytes in pneumonia: Functional plasticity and innate memory (Review).International journal of molecular medicine · 2026Review
- Humanizing acidic mammalian chitinase variants establish lung immune conditioning and control environmentally driven inflammation and fibrosis.Cell reports · 2026Article
- An immune-poised state of human bronchial epithelial cells mediates defense against RSV in adults.Nature communications · 2026Article
- Trimodal, uncertainty-guided whole-slide framework for genome-scale spatial expression and image-only virtual perturbation in cancer cohorts.Genome medicine · 2026Article
- Combination of Ophiopogonin D, Ginsenoside Rg1, and Ginsenoside Rg3 ameliorates idiopathic pulmonary fibrosis via inhibiting type 2 alveolar epithelial cell senescence and epithelial-mesenchymal transition.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Murine models of pulmonary fibrosis: mechanisms, limitations and translational insights.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66cAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- Longitudinal clinical proteomics reveals pneumonia type-specific protein biomarkers and autoantibodies.JCI insight · 2026Article
- Host-Pathogen Interactions Leading to Pneumonia Pathogenesis.Clinics in chest medicine · 2026Review
- Fibroblasts as regulators of lung immunity, repair and fibrosis.Nature reviews. Immunology · 2026Review
- Hallmarks of the ageing lung: 10 years later.The European respiratory journal · 2026Review
- Beyond the epithelium: multicellular niches in lung regeneration and disease.American journal of physiology. Lung cellular and molecular physiology · 2026Review
- GLIS3 marks a neural-like progenitor cell state that drives metastasis in pancreatic ductal adenocarcinoma.Cell reports · 2026Article
- A CD54-targeted magneto-responsive nanotheranostic for precision treatment of viral pneumonia via CTSB-mediated PANoptosis inhibition.Journal of nanobiotechnology · 2026Article
- Chronic TGFβ1 Signaling Drives Aberrant Alveolar-Basaloid Metaplasia through a KRT17-Stratifin migratory complex.bioRxiv : the preprint server for biology · 2026Article
- Article
- Profibrotic macrophage populations and cell communications in pulmonary fibrosis.Journal of physiology and biochemistry · 2026Review
- Article
- Spatial and cellular composition of lung fibrosis induced by multi-walled carbon nanotubes.Journal of nanobiotechnology · 2026Article
Corrections and comments
- Update of
Authors and funding
34 authors.
Harish Narasimhan *Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0002-3376-8257
In Su Cheon *Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Wei Qian *Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Sheng'en Shawn Hu *Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA.ORCID 0000-0002-9691-7344
Tanyalak Parimon *Women's Guild Lung Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Chaofan LiBeirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0002-5426-1498
Nick GoplenRobert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0003-4614-5996
Yue WuBeirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0003-3667-2960
Xiaoqin WeiBeirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Young Min SonDepartment of Systems Biotechnology, Chung-Ang University, Anseong, Korea.
Elizabeth FinkBeirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Gislane de Almeida SantosBeirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0002-9605-2061
Jinyi TangBeirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Changfu YaoWomen's Guild Lung Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0003-1357-5017
Lyndsey MuehlingDivision of Asthma, Allergy and Immunology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0003-3203-3264
Glenda CanderanDivision of Asthma, Allergy and Immunology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
Alexandra KadlDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
Abigail CannonBeirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Samuel YoungBeirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Riley HannanDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
Grace BinghamDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.
Mohammed ArishBeirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Arka Sen ChaudhariBeirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0001-6771-3089
Jun Sub ImBeirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Cameron L R MattinglyDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Patcharin PramoonjagoSchool of Medicine, University of Virginia, Charlottesville, VA, USA.
Alberto MarchesvskyDepartment of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Jeffrey SturekDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0002-2731-3299
Jacob E KohlmeierDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0002-7209-6641
Yun Michael ShimDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
Judith WoodfolkDivision of Asthma, Allergy and Immunology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
Chongzhi ZangCenter for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA. zang@virginia.edu.ORCID 0000-0003-4812-3627
Peter ChenWomen's Guild Lung Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Peter.Chen@cshs.org.ORCID 0000-0002-5330-1718
Jie SunBeirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA. js6re@virginia.edu.ORCID 0000-0002-2347-4511
Funding
INTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007496 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Michael G. Brown, Coleen A McNamara · 1995 to 2026
$10.2MCellular and molecular programming of lung resident T cell memoryR35HL150803 · NHLBI · EMORY UNIVERSITY · PI JACOB E KOHLMEIER · 2020 to 2026
$5.4MHost cellular network governing the development of post SARS-CoV-2 tissue sequelaeR01AI147394 · NIAID · UNIVERSITY OF VIRGINIA · PI Jie Sun · 2020 to 2026
$4.7MMolecular regulation of protective CD8 immunity against influenza infectionR01AI112844 · NIAID · UNIVERSITY OF VIRGINIA · PI SUN, JIE · 2015 to 2024
$4.5MHyperpolarized Xenon-129 MRI: a new multi-dimensional biomarker to determine pulmonary physiologic responses to COPD therapeuticsR01HL132177 · NHLBI · UNIVERSITY OF VIRGINIA · PI QING, KUN, SHIM, YUN MICHAEL · 2017 to 2021
$3.9MElucidating the roles of alveolar macrophage inflammation and selfrenewal during influenza infectionR01AG069264 · NIA · UNIVERSITY OF VIRGINIA · PI Jie Sun · 2020 to 2026
$3.5MIntegrative computational models for functional epigenomics and transcriptional regulationR35GM133712 · NIGMS · UNIVERSITY OF VIRGINIA · PI Chongzhi Zang · 2019 to 2026
$3.4MSexual dimorphism in susceptibility to emphysematous tissue injuryR01HL167202 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI ANI Wang MANICHAIKUL, Yun Michael Shim · 2023 to 2026
$3.0MRoles of tissue-resident helper T cells in mucosal immunity against influenzainfectionR01AI154598 · NIAID · UNIVERSITY OF VIRGINIA · PI SUN, JIE · 2020 to 2024
$2.9MDeterminants of Convalescent and Vaccine-induced Mucosal Specific Immunity to SARS-CoV-2 and Variants of Concern in Children with AsthmaR01AI176171 · NIAID · UNIVERSITY OF VIRGINIA · PI Jie Sun, WILLIAM GERALD TEAGUE · 2023 to 2026
$2.7MUncover mechanisms underlying the development of chronic lung sequelae post COVID-19R01HL170961 · NHLBI · UNIVERSITY OF VIRGINIA · PI Jie Sun, ROBERT VASSALLO · 2023 to 2026
$2.7MSyndecan-1 suppression of lung inflammation - Diversity SupplementR01HL159953 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI CHEN, PETER · 2022 to 2025
$2.7MNHLBI NIH HHS F31 HL164049NHLBI NIH HHS F31 HL170746NHLBI NIH HHS R01 HL132177NHLBI NIH HHS R01 HL132287NHLBI NIH HHS R01 HL155759NHLBI NIH HHS R01 HL159953NHLBI NIH HHS R01 HL167202NHLBI NIH HHS R01 HL170961NHLBI NIH HHS R35 HL150803NIAID NIH HHS R01 AI112844NIAID NIH HHS R01 AI147394NIAID NIH HHS R01 AI154598NIAID NIH HHS R01 AI176171NIAID NIH HHS R56 AI178669NIAID NIH HHS T32 AI007496NIA NIH HHS R01 AG047156NIA NIH HHS R01 AG069264NIA NIH HHS R01 AG090337NIGMS NIH HHS R35 GM133712
Abstract
The long-term physiological consequences of respiratory viral infections, particularly in the aftermath of the COVID-19 pandemic-termed post-acute sequelae of SARS-CoV-2 (PASC)-are rapidly evolving into a major public health concern
Indexed as
Epithelial CellsLungPost-Acute COVID-19 SyndromePulmonary FibrosisStem Cell NicheAnimalsCD8-Positive T-LymphocytesCohort StudiesDisease Models, AnimalFemaleGene Expression ProfilingHumansInterferon-gammaInterleukin-1betaMacrophagesMiceInterferon-gammaInterleukin-1betaTumor Necrosis Factor-alpha
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.