ArticleScientific reports2024
Association between the C-reactive protein to albumin ratio with asthma and mortality in adult: a population-based study.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Lactate-to-albumin ratio, C-reactive protein-to-albumin ratio, and prognostic nutritional index in acute and critical care: A focused mini-review.World journal of critical care medicine · 2026Review
- Predicting severe community-acquired pneumonia in adults: a machine learning approach using C-reactive protein to albumin ratio.Journal of thoracic disease · 2025Article
- Association of neutrophil percentage-to-albumin ratio with all-cause and respiratory disease-related mortality in US adults with asthma.BMC pulmonary medicine · 2025Article
- Vitamin D as a Key Mediator Between C-reactive Protein to Albumin Ratio and Congestive Heart Failure in an Elderly Population: An Innovative Exploration Using the NHANES Database.Reviews in cardiovascular medicine · 2025Article
- Association of oxidative balance scores with cardiovascular and all cause mortality in patients with asthma.Scientific reports · 2025Article
- Association between C-reactive protein to albumin ratio and chronic obstructive pulmonary disease: a cross-sectional study.BMC pulmonary medicine · 2025Article
- Association between the CALLY index, vitamin D, and asthma: insights from NHANES.Frontiers in allergy · 2025Article
- The C-reactive protein-to-albumin ratio as a diagnostic biomarker for rheumatoid arthritis: a cross-sectional NHANES analysis.Frontiers in medicine · 2025Article
- Protective effect of dietary phosphorus intake on cardiovascular mortality in asthma: evidence from NHANES 1999-2018.Frontiers in nutrition · 2025Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma is a prevalent chronic disease characterized by airflow obstruction, causing breathing difficulties and wheezing. This study investigates the association between the C-reactive protein to albumin ratio (CAR) and asthma prevalence, as well as all-cause and respiratory mortality among asthma patients, using data from the 2001-2018 National Health and Nutrition Examination Survey. We included participants aged 20 years and older with complete CAR data, excluding those who were pregnant or lost to follow-up. The analysis employed weighted logistic regression and Cox proportional hazards models with stepwise adjustment, restricted cubic spline analysis for nonlinear relationships, and time-dependent ROC curves for predictive accuracy. Results showed that the highest CAR quartile significantly increased the risk of asthma (OR 1.56, 95% CI 1.38-1.78), all-cause mortality (HR 2.20, 95% CI 1.67-2.89), and respiratory mortality (HR 2.56, 95% CI 1.30-5.38). The impact of CAR on all-cause mortality was particularly significant in hypertensive patients. These findings highlight CAR's potential as a valuable biomarker for predicting asthma prevalence and mortality, underscoring its role in asthma management and prognostication.
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