Evidence map›Paper›PMID 39232012›Full record

ArticleScientific reports2024

Macular vascular and photoreceptor changes for diabetic macular edema at early stage.

Qinyuan Gu, Ting Pan, Ruiwen Cheng, Junlong Huang, Kang Zhang, Junyan Zhang, Yang Yang, Peng Cheng, Qinghuai Liu, Han Shen

Registry-linked trialAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07232225 (OCT-Based Screening for Early Retinal Changes in Asymptomatic Diabetic Patients), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07232225 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

OCT-Based Screening for Early Retinal Changes in Asymptomatic Diabetic Patients

TypeobservationalSponsorAssiut UniversityRan2025 to 2027Enrolled112ConditionsDiabetic Macular EdemaArmsSpectral Domain OCT Imaging
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qinyuan Gu *Department of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, Nanjing, 210029, China.
Ting Pan *Department of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, Nanjing, 210029, China.
Ruiwen ChengDepartment of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, Nanjing, 210029, China.
Junlong HuangDepartment of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, Nanjing, 210029, China.
Kang ZhangDepartment of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, Nanjing, 210029, China.
Junyan ZhangDepartment of Clinical Epidemiology and Evidence-Based Medicine, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, 030032, China.
Yang YangDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei, China. carlayangyang@whu.edu.cn.
Peng ChengDepartment of Gerontology, The First Affiliated Hospital With Nanjing Medical University, Nanjing, 210029, China. cphh@sohu.com.
Qinghuai LiuDepartment of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, Nanjing, 210029, China. liuqh@njmu.edu.cn.
Han ShenDepartment of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, Nanjing, 210029, China. shenhan@njmu.edu.cn.

Funding

National Natural Science Foundation of China 82101151National Natural Science Foundation of China 82271100Natural Science Foundation of Jiangsu Province BK20210972
6 · The paper itself

Abstract

This study was intended to investigate the macular vascular and photoreceptor changes for diabetic macular edema (DME) at the early stage. A total of 255 eyes of 134 diabetes mellitus patients were enrolled and underwent an ophthalmological and systemic evaluation in this cross-sectional study. Early DME was characterized by central subfoveal thickness (CST) value between 250 and 325 μm, intact ellipsoid zone, and an external limiting membrane. While non-DME was characterized by CST < 250 μm with normal retinal morphology and structure. Foveal avascular zone (FAZ) area ≤ 0.3 mm

Indexed as

Diabetic RetinopathyMacular EdemaRetinal VesselsAgedCross-Sectional StudiesFemaleFovea CentralisHumansMacula LuteaMaleMiddle AgedTomography, Optical CoherenceAdaptive optics scanning laser ophthalmoscopeDiabetic macular edemaFoveal avascular zoneOptical coherence tomography angiography

Identifiers

PMID39232012
PMCPMC11374796

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.