SynthesisAIDS and behavior2025
Health Outcomes Associated with Loneliness and Social Isolation in Older Adults Living with HIV: A Systematic Review.
Synthesis in AIDS and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of Loneliness and Social Isolation Among People Living With HIV: A Systematic Review and Meta-Analysis.Journal of clinical nursing · 2026Pooled it
- Social isolation and loneliness effects on medication adherence in older adults: perspectives from a systematic review.BMC public health · 2026Pooled it
- The GrimAge clock corresponds to brain ageing and social determinants of health in people with HIV.EBioMedicine · 2026Article
- Associations of Trajectories of Loneliness and Neighborhood Stability with Depression, Alcohol and Substance Use, and Quality of Life among Women Living with HIV.medRxiv : the preprint server for health sciences · 2026Article
- Experiences With Technology Among Adults Aging With HIV Engaged in an Online Community-Based Exercise Intervention Study: Longitudinal Qualitative Descriptive Study and Secondary Data Analysis.JMIR rehabilitation and assistive technologies · 2026Article
- AFLE-HIV: developing an age-friendly living environment assessment framework for elderly HIV-infected individuals in China.BMC public health · 2026Article
- Resilience, and Personality Traits as Independent Correlates of Perceived Treatment Management Abilities in Middle-Aged and Older People Living with HIV.AIDS and behavior · 2026Article
- Relationship between self-perceptions of ageing and interoception among older people living with HIV: a latent profile analysis.BMC public health · 2026Article
- Current perspectives and emerging directions in research and practice: highlights from the 15th Annual International Workshop on Aging and HIV.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Exploring frailty in the context of HIV and aging in Kazakhstan: findings from a pilot cross-sectional study.BMC public health · 2026Article
- Impact of HIV-related stigma on quality of life among people with HIV: evidence from Dar es Salaam, Tanzania.AIDS care · 2026Article
- Lived Experiences of Social Isolation and Meaningful Relationships Among Older Adults Living with HIV with a Concurrent Mental Health Diagnosis: A Heideggerian Phenomenological Approach.Healthcare (Basel, Switzerland) · 2026Article
- Social Determinants of Health and HIV Diagnosis Rates in U.S. Counties, Comparing Ending the Epidemic (EHE) and Non-EHE Priority Jurisdictions.AIDS and behavior · 2026Article
- Ageing, health system implications, and a changing epidemic: organizational transitions and stigma dynamics in Philippine HIV care.Frontiers in public health · 2026Review
- Geriatric syndromes in women living with HIV.Current opinion in HIV and AIDS · 2026Review
- Loneliness as a sex-specific risk factor for cognitive aging.Frontiers in human neuroscience · 2026Review
- Hormonal and Behavioral Consequences of Social Isolation and Loneliness: Neuroendocrine Mechanisms and Clinical Implications.International journal of molecular sciences · 2025Review
- What are the key targets to improve quality of life among MSM living with HIV on antiretroviral therapy? A network analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Psychological resilience and social support as determinants of HIV-related stress in older adults living with HIV in China: a moderated mediation analysis.BMC public health · 2025Article
- Experiences, Challenges, and Needs of People Living with HIV in Hunan Province, China: A Qualitative Study.Journal of multidisciplinary healthcare · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Self-management of HIV is crucial to reduce disease-related negative health outcomes. Loneliness and social isolation are associated with poor disease self-management (e.g., medication non-adherence and care disengagement) in younger people with HIV and negative health outcomes in the general older adult population. Older adults with HIV (OWH) are at increased risk for loneliness and social isolation, but the associated health outcomes remain unclear. A comprehensive review of Pubmed, Embase, PsycINFO, and Web of Science databases was conducted. Criteria for inclusion were original quantitative research, published in the English language, included adults with a mean age ≥ 50 years, and included a measure for loneliness or social isolation, and a health outcome measure. A total of 41 studies were analyzed and 19,282 participants contributed to this review. The main findings were that loneliness and social isolation were associated with negative health behavior, disease self-management, physiological, and psychological outcomes. Pooled prevalence of loneliness was 33.9% across 8 studies. Loneliness and social isolation are highly prevalent in OWH and are associated with negative outcomes in OWH, similarly to older adults in the general population. Older adults with HIV, however, are challenged by unique psychosocial circumstances that place them at greater risk for loneliness and social isolation and associated negative health outcomes. These findings should be verified in larger, diverse, and longitudinal samples to better understand interrelationships of psychosocial factors and clinical outcomes in OWH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.