Evidence map›Paper›PMID 39231831›Full record

ArticleArchives of gynecology and obstetrics2024

Required number of blastocysts transferred, and oocytes retrieved to optimize live and cumulative live birth rates in the first complete cycle of IVF for autologous and donated oocytes.

Sandra P Cubillos-García, Francisco Revilla-Pacheco, Marcos Meneses-Mayo, Rosa E Rodríguez-Guerrero, Silvio Cuneo-Pareto

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Article in Archives of gynecology and obstetrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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  4. Review
  5. EnhancingGynecology and minimally invasive therapy
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sandra P Cubillos-GarcíaCONCIBE Reproducción Asistida, Avenida paseo de las palmas 745, nº 405, 11000, CDMX, México. spcubillos@yahoo.com.ORCID 0000-0003-3487-8738
Francisco Revilla-PachecoFacultad de Ciencias de la Salud, Universidad Anáhuac México Norte, Huixquilucan, Estado de México, México.ORCID 0000-0002-1290-6139
Marcos Meneses-MayoFacultad de Ciencias de la Salud, Universidad Anáhuac México Norte, Huixquilucan, Estado de México, México.ORCID 0000-0001-7214-2030
Rosa E Rodríguez-GuerreroCONCIBE Reproducción Asistida, Avenida paseo de las palmas 745, nº 405, 11000, CDMX, México.ORCID 0000-0003-1341-2576
Silvio Cuneo-ParetoCONCIBE Reproducción Asistida, Avenida paseo de las palmas 745, nº 405, 11000, CDMX, México.ORCID 0000-0001-8590-5041

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate live birth rate (LBR) and cumulative live birth rate (CLBR) to achieve the first newborn per blastocyst transferred and oocyte retrieved in the first complete IVF cycle of autologous and donated oocytes and identify the possible success factors.

methodsThis was a retrospective cohort study of a private IVF center. There were 1867 cycles, 1241 of which were fresh transfers and 626, their subsequent thawing transfers.

resultsWe found significant variables by binary logistic regression. For LBR, female infertility and the day of blastocyst transferred were relevant; however, for CLBR, the numbers of blastocysts available for future transfers, oocyte age, and maternal age were more critical. Oocyte age is a negative factor that begins to affect CLBR gradually beyond 36 years; from that age, there are significant worse results in polycystic ovary syndrome and poor responder patients.

conclusionThe LBR and CLBR were optimized for oocyte recipients when eight oocytes were retrieved (63.6%; 87.9%); at most, fourteen oocytes should be assigned to avoid freezing surplus blastocysts. Thirteen autologous oocytes (69.2%; 92.3%) were ideal for optimization. CLBR optimized after three blastocysts in donor oocytes (81.8%) and four for autologous oocyte patients (80.9%). Our outcomes are valuable for doctors and infertile couples, and they give us information on what we can expect from a first complete IVF cycle.

Indexed as

Birth RateEmbryo TransferFertilization in VitroLive BirthOocyte DonationOocyte RetrievalAdultBlastocystFemaleHumansInfertility, FemaleMaternal AgeOocytesPregnancyRetrospective StudiesBlastocyst transferredCumulative live birth rateFirst IVF complete cycleLive birth rateOocyte retrieved

Identifiers

PMID39231831

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.