Evidence map›Paper›PMID 39231735›Full record

ArticleJournal of advanced nursing2025

Biobehavioral Efficacy of the Elevated Side-Lying Position for Feeding Preterm Infants: Study Protocol.

Jinhee Park, Suzanne Thoyre, Jane Smallcomb, Melissa Mcternan, Tondi Kneeland

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of advanced nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04942106 (Biobehavioral Efficacy of the Semi-Elevated Side-Lying Position for Feeding Preterm Infants), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04942106 nacompletednot on this map

Biobehavioral Efficacy of the Semi-Elevated Side-Lying Position for Feeding Preterm Infants

TypeinterventionalSponsorBoston CollegeRan2022 to 2024Enrolled60ConditionsFeeding, Bottle, Infant, Premature, Diseases, Behavior, InfantArmsArm 1 - Side-lying position followed by Supine position, Arm 2 - Supine position followed by Side-lying position
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jinhee ParkBoston College William F. Connell School of Nursing, Chestnut Hill, Massachusetts, USA.ORCID https://orcid.org/0000-0002-1221-7325
Suzanne ThoyreUniversity of North Carolina at Chapel Hill School of Nursing, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0003-3180-9198
Jane SmallcombNeonatology Department, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Melissa McternanBoston College Research Services, Chestnut Hill, Massachusetts, USA.ORCID https://orcid.org/0000-0002-5151-8307
Tondi KneelandOhio State University College of Nursing, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0002-1526-7029

Funding

Biobehavioral Efficacy of the Semi-Elevated Side-Lying Position for Feeding Preterm InfantsR21NR019874 · NINR · BOSTON COLLEGE · PI PARK, JINHEE · 2021 to 2022
$469k
NINR NIH HHS R21 NR019874NINR NIH HHS R21NR019874
6 · The paper itself

Abstract

aimPresent a study protocol investigating the biobehavioral efficacy of side-lying vs. supine positions on physiologic and behavioural responses of preterm infants during their transition from tube to full oral feeding, and identify associated infant characteristics.

designWithin-subject cross-over design.

methodsSixty preterm infants born at ≤35 weeks gestational age (GA) from a level 3 NICU are observed during their transition to full oral feeding. Each undergoes two feedings within 24 h: One in the supine position and one in the side-lying position. Continuous physiologic and video data are collected 30 min before and after feeding. Physiologic measures include heart rate, respiratory rate, oxygen saturation, and autonomic nervous system regulation (heart rate variability and splanchnic-cerebral oxygen ratio). Behavioural responses are assessed via microanalysis of the sucking and breathing waveforms and videotaped feedings (Suck-breathe coordination and Early Feeding Skills assessment tool). Data are analysed using linear mixed-effects models. IRB was obtained in September 2021, with funding awarded by the National Institute of Nursing Research in July 2021.

conclusionThis study will enhance our understanding of the effects of the side-lying position on preterm infant feeding, providing guidance for its clinical use as a feeding strategy. IMPLICATIONS: Provides vital knowledge to guide evidence-based practices in enhancing oral feeding in preterm infants and inform future pivotal efficacy trials. IMPACT: If effective, this intervention could significantly enhance the management of feeding challenges in preterm infants across neonatal care settings. REPORTING

methodStandard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2013. PATIENT OR PUBLIC CONTRIBUTION: While direct parent involvement was not documented in our protocol, informal feedback on data collection procedures from parents was incorporated. Additionally, extensive engagement with healthcare professionals during study design addressed patient safety, logistical challenges, and ethical standards in NICU settings.

trial registrationClinicalTrials.gov identifier: NCT04942106; registered on 28 June 2021. Available at: https://clinicaltrials.gov/ct2/show/NCT04942106.

Indexed as

Feeding BehaviorInfant, PrematurePatient PositioningPostureCross-Over StudiesFemaleHumansInfant BehaviorInfant, NewbornIntensive Care Units, NeonatalMaleRandomized Controlled Trials as TopicSupine Positionfeedingneonatal intensive carepositioningpreterm infantstress

Identifiers

PMID39231735
PMCPMC11876459

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.