Evidence map›Paper›PMID 39231678›Full record

ReviewInternal medicine (Tokyo, Japan)2025

Cognitive Dysfunction as an Initial Manifestation of Rheumatoid Arthritis-associated Intravascular Large B-cell Lymphoma.

Junya Kitai, Ryuichi Minoda Sada, Satoko Yamaguchi, Akiyo Shinde, Wataru Maruyama

Abstract readCase ReportsReview
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Junya KitaiDepartment of General Internal Medicine, Tenri Hospital, Japan.
Ryuichi Minoda SadaDepartment of General Internal Medicine, Tenri Hospital, Japan.
Satoko YamaguchiDepartment of Neurology, Tenri Hospital, Japan.
Akiyo ShindeDepartment of Neurology, Tenri Hospital, Japan.
Wataru MaruyamaDepartment of Hematology, Tenri Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 58-year-old Japanese woman with rheumatoid arthritis (RA) presented with the sudden onset of cognitive dysfunction. A random skin biopsy revealed intravascular large B-cell lymphoma (IVLBCL), which resolved spontaneously with methotrexate withdrawal. However, four months later, the disease relapsed with liver injury. After completion of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone therapy, both RA and IVLBCL remained in remission for two years. Among the pathological subtypes of RA-associated lymphoproliferative diseases, reports on IVLBCL are limited, and little is known about its clinical course. Our literature review summarizes the clinical course and mortality of 11 patients with RA-IVLBCL.

Indexed as

Arthritis, RheumatoidCognitive DysfunctionLymphoma, Large B-Cell, DiffuseVascular NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsDoxorubicinFemaleHumansMiddle AgedRituximabVincristineDoxorubicinRituximabVincristinecognitive dysfunctionintravascular large B-cell lymphomalymphoproliferative disordermethotrexaterheumatoid arthritis

Identifiers

PMID39231678
PMCPMC12097827

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.