Evidence map›Paper›PMID 39231596›Full record

SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2024

Adherence-enhancing interventions for pharmacological and oxygen therapy in patients with COPD: a systematic review and component network meta-analyses.

Omar Ammous, Regina Kampo, Maximilian Wollsching-Strobel, Maximilian Zimmermann, Stefan Andreas, Tim Friede, Doreen Kroppen, Sarah Stanzel, Susanna Salem, Wolfram Windisch and 1 more

Abstract readSystematic ReviewNetwork Meta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Omar AmmousDepartment of Medical Statistics, University Medical Center Göttingen, Göttingen, Germany omar.ammous@med.uni-goettingen.de.ORCID https://orcid.org/0000-0003-1671-1432
Regina KampoDepartment of Medical Statistics, University Medical Center Göttingen, Göttingen, Germany.
Maximilian Wollsching-StrobelCologne Merheim Hospital, Department of Pneumology, Kliniken der Stadt Köln gGmbH, Cologne, Germany.ORCID https://orcid.org/0000-0003-2302-7284
Maximilian ZimmermannCologne Merheim Hospital, Department of Pneumology, Kliniken der Stadt Köln gGmbH, Cologne, Germany.
Stefan AndreasLungenfachklinik Immenhausen/Krs. Kassel, Clinic for Cardiology and Pneumology, University Medical Center Göttingen, Göttingen, Germany.ORCID https://orcid.org/0000-0003-3918-6909
Tim FriedeDepartment of Medical Statistics, University Medical Center Göttingen, Göttingen, Germany.ORCID https://orcid.org/0000-0001-5347-7441
Doreen KroppenCologne Merheim Hospital, Department of Pneumology, Kliniken der Stadt Köln gGmbH, Cologne, Germany.
Sarah StanzelCologne Merheim Hospital, Department of Pneumology, Kliniken der Stadt Köln gGmbH, Cologne, Germany.ORCID https://orcid.org/0000-0001-8989-0211
Susanna SalemDepartment of Medical Statistics, University Medical Center Göttingen, Göttingen, Germany.
Wolfram WindischCologne Merheim Hospital, Department of Pneumology, Kliniken der Stadt Köln gGmbH, Cologne, Germany.
Tim MathesDepartment of Medical Statistics, University Medical Center Göttingen, Göttingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAdherence to COPD management strategies is complex, and it is unclear which intervention may enhance it.

objectivesWe aim to evaluate the effectiveness of adherence-enhancing interventions, alone or compared to interventions, for patients with COPD.

methodsThis review comprises a component network meta-analysis with a structured narrative synthesis. We searched MEDLINE, Embase, CENTRAL, CINAHL and trial registries on 9 September 2023. We included controlled studies that explored adherence in patients with COPD. Two review authors independently performed the study selection, data extraction and the risk of bias assessment. We involved patients with COPD in developing this systematic review through focus group interviews and displayed the findings in pre-designed logic models.

resultsWe included 33 studies with 5775 participants. We included 13 studies in the component network meta-analysis that explored adherence. It was mainly assessed through questionnaires. As a continuous outcome, there was a tendency mainly for education (standardised mean difference 1.26, 95% CI 1.13-1.38, very low certainty of evidence) and motivation (mean difference 1.85, 95% CI 1.19-2.50, very low certainty of evidence) to improve adherence. As a dichotomous outcome (

conclusionsEducation may improve adherence and quality of life in COPD patients. Patient focus group interviews indicated that interventions that strengthen patients' self-efficacy and help them to achieve individual goals are the most helpful.

Indexed as

Oxygen Inhalation TherapyPulmonary Disease, Chronic ObstructiveFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMedication AdherenceMotivationPatient CompliancePatient Education as TopicQuality of LifeTreatment Outcome

Identifiers

PMID39231596
PMCPMC11372468

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.