Evidence map›Paper›PMID 39231392›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2024

New Benchmark for Targeted Therapies in Lung Cancer: Median Progression-Free Survival for Lorlatinib in Advanced ALK+ Non-Small Cell Lung Cancer Surpasses 5 years.

Christine M Lovly

Abstract readEditorialComment
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Christine M LovlyDivision of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN.ORCID 0000-0002-3641-6361

Funding

The Role of Focal Oncogene Amplifications in Lung CancerP01CA129243 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Marc Ladanyi · 2007 to 2026
$31.2M
ECOG-ACRIN Thoracic Malignancies Integrated Translational Science CenterUG1CA233259 · NCI · EMORY UNIVERSITY · PI CARBONE, DAVID P., LEAL, TICIANA · 2019 to 2025
$5.1M
Mechanistic insights into Variants of Uncertain Significance (VUS) using novel EGFR variants as a paradigmR01CA227833 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI LOVLY, CHRISTINE M., MEILER, JENS · 2019 to 2023
$1.7M
Phenotype Interactions in SCLC Development and DetectionU01CA224276 · NCI · VANDERBILT UNIVERSITY · PI WEAVER, ALISSA M · 2018 to 2022
$1.6M
NCI NIH HHS P01 CA129243NCI NIH HHS R01 CA227833NCI NIH HHS U01 CA224276NCI NIH HHS UG1 CA233259
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AminopyridinesAnaplastic Lymphoma KinaseCarcinoma, Non-Small-Cell LungLactamsLactams, MacrocyclicLung NeoplasmsProgression-Free SurvivalPyrazolesFemaleHumansMaleMolecular Targeted TherapyProtein Kinase InhibitorsALK protein, humanAminopyridinesAnaplastic Lymphoma KinaseLactamsLactams, MacrocycliclorlatinibProtein Kinase InhibitorsPyrazoles

Identifiers

PMID39231392
PMCPMC11521153

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.