Evidence map›Paper›PMID 39231205›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

High-resolution stereolithography: Negative spaces enabled by control of fluid mechanics.

Ian A Coates, William Pan, Max A Saccone, Gabriel Lipkowitz, Dan Ilyin, Madison M Driskill, Maria T Dulay, Curtis W Frank, Eric S G Shaqfeh, Joseph M DeSimone

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ian A CoatesDepartment of Chemical Engineering, Stanford University, Stanford, CA 94305.ORCID 0000-0002-8853-1505
William PanDepartment of Mechanical Engineering, Stanford University, Stanford, CA 94305.
Max A SacconeDepartment of Chemical Engineering, Stanford University, Stanford, CA 94305.ORCID 0000-0003-3846-2908
Gabriel LipkowitzDepartment of Mechanical Engineering, Stanford University, Stanford, CA 94305.ORCID 0000-0003-4869-6804
Dan IlyinDepartment of Mechanical Engineering, Stanford University, Stanford, CA 94305.
Madison M DriskillDepartment of Chemical Engineering, Stanford University, Stanford, CA 94305.
Maria T DulayDepartment of Radiology, Stanford University, Stanford, CA 94305.
Curtis W FrankDepartment of Chemical Engineering, Stanford University, Stanford, CA 94305.
Eric S G ShaqfehDepartment of Chemical Engineering, Stanford University, Stanford, CA 94305.ORCID 0000-0001-8241-2946
Joseph M DeSimoneDepartment of Chemical Engineering, Stanford University, Stanford, CA 94305.

Funding

Bill and Melinda Gates Foundation (GF) INV-046940
6 · The paper itself

Abstract

Stereolithography enables the fabrication of three-dimensional (3D) freeform structures via light-induced polymerization. However, the accumulation of ultraviolet dose within resin trapped in negative spaces, such as microfluidic channels or voids, can result in the unintended closing, referred to as overcuring, of these negative spaces. We report the use of injection continuous liquid interface production to continuously displace resin at risk of overcuring in negative spaces created in previous layers with fresh resin to mitigate the loss of Z-axis resolution. We demonstrate the ability to resolve 50-μm microchannels, breaking the historical relationship between resin properties and negative space resolution. With this approach, we fabricated proof-of-concept 3D free-form microfluidic devices with improved design freedom over device material selection and resulting properties.

Indexed as

3D-printingmicrofluidicsnegative-spacestereolithographyvat-polymerization

Identifiers

PMID39231205
PMCPMC11406279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.