Evidence map›Paper›PMID 39231190›Full record

ArticleGenes, brain, and behavior2024

Commensal bacteria exacerbate seizure-like phenotypes in Drosophila voltage-gated sodium channel mutants.

Patrick Lansdon, Junko Kasuya, Toshihiro Kitamoto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, brain, and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patrick LansdonInterdisciplinary Graduate Program in Genetics, Graduate College, University of Iowa, Iowa City, Iowa, USA.
Junko KasuyaDepartment of Anesthesia, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Toshihiro KitamotoInterdisciplinary Graduate Program in Genetics, Graduate College, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0003-0863-8466

Funding

Interdisciplinary Training Program in Pain ResearchT32NS045549 · NINDS · UNIVERSITY OF IOWA · PI KATHLEEN A SLUKA, Yuriy M Usachev · 2004 to 2026
$3.7M
A death-independent function for RIPK3 signaling in neuroinflammationR21NS101542 · NINDS · UNIVERSITY OF WASHINGTON · PI OBERST, ANDREW ATWELL · 2017 to 2018
$483k
Roles of hemocytes and bioactive lipids in the modulation of neuronal excitability and seizure behavior in Drosophila voltage-gated sodium channel mutantsR21NS127364 · NINDS · UNIVERSITY OF IOWA · PI KITAMOTO, TOSHIHIRO · 2022 to 2023
$425k
Modulation of neurological phenotypes by the gut microbiota in DrosophilaR21NS101545 · NINDS · UNIVERSITY OF IOWA · PI KITAMOTO, TOSHIHIRO · 2017 to 2018
$419k
Genetic suppression of seizure-like phenotypes in a Drosophila model of epilepsyR03NS101541 · NINDS · UNIVERSITY OF IOWA · PI KITAMOTO, TOSHIHIRO · 2017 to 2018
$153k
NIH HHS R03 NS101541NIH HHS R21 NS101542NIH HHS R21 NS127364NIH HHS T32 NS045549NINDS NIH HHS R03 NS101541NINDS NIH HHS R21 NS101542NINDS NIH HHS R21 NS101545NINDS NIH HHS R21 NS127364NINDS NIH HHS T32 NS045549
6 · The paper itself

Abstract

Mutations in voltage-gated sodium (Na

Indexed as

SeizuresVoltage-Gated Sodium ChannelsAcetobacterAnimalsDrosophila melanogasterDrosophila ProteinsGastrointestinal MicrobiomeMutationNF-E2-Related Factor 2PhenotypeSymbiosisDrosophila ProteinsNF-E2-Related Factor 2Voltage-Gated Sodium Channelscommensal bacteriaDrosophila melanogastergut‐brain connectionNrf2seizurevoltage‐gated sodium channel

Identifiers

PMID39231190
PMCPMC11373613

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.