Evidence map›Paper›PMID 39231018›Full record

ArticleJournal of veterinary internal medicine

Urinary iodine clearance after iodinated contrast administration to healthy cats.

Gabriella Allegrini, Valerie J Poirier, Julia G Pezzali, Hughes H Beaufrère, Anna K Shoveller, Matthew A Kopke, Janet Beeler-Marfisi

Abstract read
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In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gabriella AllegriniAnimal Cancer Centre, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.
Valerie J PoirierAnimal Cancer Centre, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.ORCID https://orcid.org/0000-0002-0170-3934
Julia G PezzaliDepartment of Animal Biosciences, Ontario Agricultural College, University of Guelph, Guelph, Ontario, Canada.
Hughes H BeaufrèreDepartment of Veterinary Medicine and Epidemiology, University of California Davis, School of Veterinary Medicine, Davis, California, USA.
Anna K ShovellerDepartment of Animal Biosciences, Ontario Agricultural College, University of Guelph, Guelph, Ontario, Canada.
Matthew A KopkeVeterinary Nutrition Group, Sydney, New South Wales, Australia.
Janet Beeler-MarfisiDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.

Funding

OVC Pet Trust 055180
6 · The paper itself

Abstract

backgroundExogenous iodine interferes with the uptake of radioactive iodine ( HYPOTHESIS: To determine the time to normalize urinary iodine clearance after administration of ICM. We hypothesized that it would require 4 weeks for urinary iodine concentration (UIC) to decrease to baseline after IV administration of ICM. ANIMALS: Ten healthy adult neutered male cats.

methodsAll cats were sedated and received Iopamidol at a dose of 2 mL/kg (600 mg/kg). Urinary iodine and creatinine concentrations were measured before administration of Iopamidol and on days 1, 2, 3, 7, 10 and weeks 2 to 6 after administration. The urinary iodine-to-creatinine ratio (UICR) was calculated. Outcome variables were modeled using a linear mixed-effects model.

resultsUrinary iodine concentration increased 37- to 884-fold on Day 1 after ICM injection and returned to baseline during Week 2. Compared with baseline, UIC was significantly increased for Days 1 to 7 (all P < .001); UC was significantly lower for Days 1 to 10 (all P < .03); and UICR was significantly increased from Days 1 to 10 (all P < .001, except Day 10 P = .05).

conclusionsUrinary clearance of iodine after IV administration of ICM requires 10 days to return to baseline in healthy cats. A 2-week interval between the iodinated contrast study and

Indexed as

Contrast MediaCreatinineIodineIopamidolAnimalsCatsIodine RadioisotopesMaleContrast MediaCreatinineIodineIodine RadioisotopesIopamidol131Ihyperthyroidismiodinated contrastiodine clearanceradioactive iodineurinary iodine

Identifiers

PMID39231018
PMCPMC11423442

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.